He XY - Search Results

1

Identification of Val117 and Arg372 as critical amino acid residues for the activity difference between human CYP2A6 and CYP2A13 in coumarin 7-hydroxylation.

He XY, Shen J, Hu WY, Ding X, Lu AY, Hong JY. He XY, et al. Arch Biochem Biophys. 2004 Jul 15;427(2):143-53. doi: 10.1016/j.abb.2004.03.016. Arch Biochem Biophys. 2004. PMID: 15196988

2

Identification of critical amino acid residues of human CYP2A13 for the metabolic activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a tobacco-specific carcinogen.

He XY, Shen J, Ding X, Lu AY, Hong JY. He XY, et al. Drug Metab Dispos. 2004 Dec;32(12):1516-21. doi: 10.1124/dmd.104.001370. Epub 2004 Aug 27. Drug Metab Dispos. 2004. PMID: 15333516

3

Metabolism of nicotine and cotinine by human cytochrome P450 2A13.

Bao Z, He XY, Ding X, Prabhu S, Hong JY. Bao Z, et al. Among authors: he xy. Drug Metab Dispos. 2005 Feb;33(2):258-61. doi: 10.1124/dmd.104.002105. Epub 2004 Nov 4. Drug Metab Dispos. 2005. PMID: 15528319

4

The missense genetic polymorphisms of human CYP2A13: functional significance in carcinogen activation and identification of a null allelic variant.

Wang SL, He XY, Shen J, Wang JS, Hong JY. Wang SL, et al. Among authors: he xy. Toxicol Sci. 2006 Nov;94(1):38-45. doi: 10.1093/toxsci/kfl081. Epub 2006 Aug 17. Toxicol Sci. 2006. PMID: 16917071

5

Human cytochrome p450 2s1: lack of activity in the metabolic activation of several cigarette smoke carcinogens and in the metabolism of nicotine.

Wang SL, He XY, Hong JY. Wang SL, et al. Among authors: he xy. Drug Metab Dispos. 2005 Mar;33(3):336-40. doi: 10.1124/dmd.104.002923. Epub 2004 Dec 17. Drug Metab Dispos. 2005. PMID: 15608128

6

Efficient activation of aflatoxin B1 by cytochrome P450 2A13, an enzyme predominantly expressed in human respiratory tract.

He XY, Tang L, Wang SL, Cai QS, Wang JS, Hong JY. He XY, et al. Int J Cancer. 2006 Jun 1;118(11):2665-71. doi: 10.1002/ijc.21665. Int J Cancer. 2006. PMID: 16385575

7

CYP2A13 in human respiratory tissues and lung cancers: an immunohistochemical study with a new peptide-specific antibody.

Zhu LR, Thomas PE, Lu G, Reuhl KR, Yang GY, Wang LD, Wang SL, Yang CS, He XY, Hong JY. Zhu LR, et al. Among authors: he xy. Drug Metab Dispos. 2006 Oct;34(10):1672-6. doi: 10.1124/dmd.106.011049. Epub 2006 Jun 30. Drug Metab Dispos. 2006. PMID: 16815959

8

Genetic variation of human cytochrome p450 reductase as a potential biomarker for mitomycin C-induced cytotoxicity.

Wang SL, Han JF, He XY, Wang XR, Hong JY. Wang SL, et al. Among authors: he xy. Drug Metab Dispos. 2007 Jan;35(1):176-9. doi: 10.1124/dmd.106.011056. Epub 2006 Oct 24. Drug Metab Dispos. 2007. PMID: 17062779

9

Metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) by human CYP1B1 genetic variants.

Han JF, He XY, Herrington JS, White LA, Zhang JF, Hong JY. Han JF, et al. Among authors: he xy. Drug Metab Dispos. 2008 Apr;36(4):745-52. doi: 10.1124/dmd.107.016824. Epub 2008 Jan 28. Drug Metab Dispos. 2008. PMID: 18227148

10

Effect of genetic variation on human cytochrome p450 reductase-mediated paraquat cytotoxicity.

Han JF, Wang SL, He XY, Liu CY, Hong JY. Han JF, et al. Among authors: he xy. Toxicol Sci. 2006 May;91(1):42-8. doi: 10.1093/toxsci/kfj139. Epub 2006 Feb 22. Toxicol Sci. 2006. PMID: 16495354

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