Schaffar G - Search Results

1

Cellular toxicity of polyglutamine expansion proteins: mechanism of transcription factor deactivation.

Schaffar G, Breuer P, Boteva R, Behrends C, Tzvetkov N, Strippel N, Sakahira H, Siegers K, Hayer-Hartl M, Hartl FU. Schaffar G, et al. Mol Cell. 2004 Jul 2;15(1):95-105. doi: 10.1016/j.molcel.2004.06.029. Mol Cell. 2004. PMID: 15225551 Free article.

2

Roles of molecular chaperones in protein misfolding diseases.

Barral JM, Broadley SA, Schaffar G, Hartl FU. Barral JM, et al. Among authors: schaffar g. Semin Cell Dev Biol. 2004 Feb;15(1):17-29. doi: 10.1016/j.semcdb.2003.12.010. Semin Cell Dev Biol. 2004. PMID: 15036203 Review.

3

Chaperonin TRiC promotes the assembly of polyQ expansion proteins into nontoxic oligomers.

Behrends C, Langer CA, Boteva R, Böttcher UM, Stemp MJ, Schaffar G, Rao BV, Giese A, Kretzschmar H, Siegers K, Hartl FU. Behrends C, et al. Among authors: schaffar g. Mol Cell. 2006 Sep 15;23(6):887-97. doi: 10.1016/j.molcel.2006.08.017. Mol Cell. 2006. PMID: 16973440 Free article.

4

Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils.

Muchowski PJ, Schaffar G, Sittler A, Wanker EE, Hayer-Hartl MK, Hartl FU. Muchowski PJ, et al. Among authors: schaffar g. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):7841-6. doi: 10.1073/pnas.140202897. Proc Natl Acad Sci U S A. 2000. PMID: 10859365 Free PMC article.

5

Studying interactions of four proteins in the yeast two-hybrid system: structural resemblance of the pVHL/elongin BC/hCUL-2 complex with the ubiquitin ligase complex SKP1/cullin/F-box protein.

Pause A, Peterson B, Schaffar G, Stearman R, Klausner RD. Pause A, et al. Among authors: schaffar g. Proc Natl Acad Sci U S A. 1999 Aug 17;96(17):9533-8. doi: 10.1073/pnas.96.17.9533. Proc Natl Acad Sci U S A. 1999. PMID: 10449727 Free PMC article.

6

Single particle detection and characterization of synuclein co-aggregation.

Giese A, Bader B, Bieschke J, Schaffar G, Odoy S, Kahle PJ, Haass C, Kretzschmar H. Giese A, et al. Among authors: schaffar g. Biochem Biophys Res Commun. 2005 Aug 12;333(4):1202-10. doi: 10.1016/j.bbrc.2005.06.025. Biochem Biophys Res Commun. 2005. PMID: 15978545

7

A review of the totality of evidence supporting the development and approval of a pegfilgrastim biosimilar (LA-EP2006).

Agarwala SS, Nagl U, Guo X, Bellon A, Heyn J, Dimova-Dobreva M, Shen YM, Schaffar G, Humphrey M, Mathieson N, Koptelova N, Gattu S. Agarwala SS, et al. Among authors: schaffar g. Curr Med Res Opin. 2022 Jun;38(6):999-1009. doi: 10.1080/03007995.2022.2061707. Epub 2022 Apr 17. Curr Med Res Opin. 2022. PMID: 35392751 Review.

8

Recommendations for the Development and Validation of Immunogenicity Assays in Support of Biosimilar Programs.

Civoli F, Kasinath A, Cai XY, Wadhwa M, Exley A, Oldfield P, Alvandkouhi S, Schaffar G, Chappell J, Bowsher R, Devanarayan V, Marini J, Rebarchak S, Anderson M, Koppenburg V, Lester T. Civoli F, et al. Among authors: schaffar g. AAPS J. 2019 Dec 2;22(1):7. doi: 10.1208/s12248-019-0386-y. AAPS J. 2019. PMID: 31792633

9

Nakov R, Gattu S, Wang J, Velinova M, Schaffar G, Skerjanec A. Nakov R, et al. Among authors: schaffar g. Br J Clin Pharmacol. 2018 Dec;84(12):2790-2801. doi: 10.1111/bcp.13731. Epub 2018 Sep 28. Br J Clin Pharmacol. 2018. PMID: 30079636 Free PMC article. Clinical Trial.

10

A Comparison of the Safety and Efficacy of HX575 (Epoetin Alfa Proposed Biosimilar) with Epoetin Alfa in Patients with End-Stage Renal Disease.

Weir MR, Pergola PE, Agarwal R, Fink JC, Kopyt NP, Singh AK, Kumar J, Schmitt S, Schaffar G, Rudy A, McKay JP, Kanceva R. Weir MR, et al. Among authors: schaffar g. Am J Nephrol. 2017;46(5):364-370. doi: 10.1159/000481736. Epub 2017 Oct 30. Am J Nephrol. 2017. PMID: 29084409 Free article. Clinical Trial.

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