Ciccotosto GD - Search Results

1

Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease beta-amyloid.

Barnham KJ, Haeffner F, Ciccotosto GD, Curtain CC, Tew D, Mavros C, Beyreuther K, Carrington D, Masters CL, Cherny RA, Cappai R, Bush AI. Barnham KJ, et al. Among authors: ciccotosto gd. FASEB J. 2004 Sep;18(12):1427-9. doi: 10.1096/fj.04-1890fje. Epub 2004 Jul 1. FASEB J. 2004. PMID: 15231727

2

Neurotoxic, redox-competent Alzheimer's beta-amyloid is released from lipid membrane by methionine oxidation.

Barnham KJ, Ciccotosto GD, Tickler AK, Ali FE, Smith DG, Williamson NA, Lam YH, Carrington D, Tew D, Kocak G, Volitakis I, Separovic F, Barrow CJ, Wade JD, Masters CL, Cherny RA, Curtain CC, Bush AI, Cappai R. Barnham KJ, et al. Among authors: ciccotosto gd. J Biol Chem. 2003 Oct 31;278(44):42959-65. doi: 10.1074/jbc.M305494200. Epub 2003 Aug 18. J Biol Chem. 2003. PMID: 12925530 Free article.

3

Enhanced toxicity and cellular binding of a modified amyloid beta peptide with a methionine to valine substitution.

Ciccotosto GD, Tew D, Curtain CC, Smith D, Carrington D, Masters CL, Bush AI, Cherny RA, Cappai R, Barnham KJ. Ciccotosto GD, et al. J Biol Chem. 2004 Oct 8;279(41):42528-34. doi: 10.1074/jbc.M406465200. Epub 2004 Jul 28. J Biol Chem. 2004. PMID: 15292164 Free article.

4

Gene knockout of amyloid precursor protein and amyloid precursor-like protein-2 increases cellular copper levels in primary mouse cortical neurons and embryonic fibroblasts.

Bellingham SA, Ciccotosto GD, Needham BE, Fodero LR, White AR, Masters CL, Cappai R, Camakaris J. Bellingham SA, et al. Among authors: ciccotosto gd. J Neurochem. 2004 Oct;91(2):423-8. doi: 10.1111/j.1471-4159.2004.02731.x. J Neurochem. 2004. PMID: 15447675 Free article.

5

Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42.

Crouch PJ, Blake R, Duce JA, Ciccotosto GD, Li QX, Barnham KJ, Curtain CC, Cherny RA, Cappai R, Dyrks T, Masters CL, Trounce IA. Crouch PJ, et al. Among authors: ciccotosto gd. J Neurosci. 2005 Jan 19;25(3):672-9. doi: 10.1523/JNEUROSCI.4276-04.2005. J Neurosci. 2005. PMID: 15659604 Free PMC article.

6

Methylation of the imidazole side chains of the Alzheimer disease amyloid-beta peptide results in abolition of superoxide dismutase-like structures and inhibition of neurotoxicity.

Tickler AK, Smith DG, Ciccotosto GD, Tew DJ, Curtain CC, Carrington D, Masters CL, Bush AI, Cherny RA, Cappai R, Wade JD, Barnham KJ. Tickler AK, et al. Among authors: ciccotosto gd. J Biol Chem. 2005 Apr 8;280(14):13355-63. doi: 10.1074/jbc.M414178200. Epub 2005 Jan 24. J Biol Chem. 2005. PMID: 15668252 Free article.

7

The amyloid precursor protein (APP) of Alzheimer disease and its paralog, APLP2, modulate the Cu/Zn-Nitric Oxide-catalyzed degradation of glypican-1 heparan sulfate in vivo.

Cappai R, Cheng F, Ciccotosto GD, Needham BE, Masters CL, Multhaup G, Fransson LA, Mani K. Cappai R, et al. Among authors: ciccotosto gd. J Biol Chem. 2005 Apr 8;280(14):13913-20. doi: 10.1074/jbc.M409179200. Epub 2005 Jan 27. J Biol Chem. 2005. PMID: 15677459 Free article.

8

Correlative studies support lipid peroxidation is linked to PrP(res) propagation as an early primary pathogenic event in prion disease.

Brazier MW, Lewis V, Ciccotosto GD, Klug GM, Lawson VA, Cappai R, Ironside JW, Masters CL, Hill AF, White AR, Collins S. Brazier MW, et al. Among authors: ciccotosto gd. Brain Res Bull. 2006 Jan 30;68(5):346-54. doi: 10.1016/j.brainresbull.2005.09.010. Epub 2005 Oct 5. Brain Res Bull. 2006. PMID: 16377442

9

Copper-mediated amyloid-beta toxicity is associated with an intermolecular histidine bridge.

Smith DP, Smith DG, Curtain CC, Boas JF, Pilbrow JR, Ciccotosto GD, Lau TL, Tew DJ, Perez K, Wade JD, Bush AI, Drew SC, Separovic F, Masters CL, Cappai R, Barnham KJ. Smith DP, et al. Among authors: ciccotosto gd. J Biol Chem. 2006 Jun 2;281(22):15145-54. doi: 10.1074/jbc.M600417200. Epub 2006 Apr 4. J Biol Chem. 2006. PMID: 16595673 Free article.

10

Concentration dependent Cu2+ induced aggregation and dityrosine formation of the Alzheimer's disease amyloid-beta peptide.

Smith DP, Ciccotosto GD, Tew DJ, Fodero-Tavoletti MT, Johanssen T, Masters CL, Barnham KJ, Cappai R. Smith DP, et al. Among authors: ciccotosto gd. Biochemistry. 2007 Mar 13;46(10):2881-91. doi: 10.1021/bi0620961. Epub 2007 Feb 13. Biochemistry. 2007. PMID: 17297919

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