Withers SG - Search Results

1

An unusual mechanism of glycoside hydrolysis involving redox and elimination steps by a family 4 beta-glycosidase from Thermotoga maritima.

Yip VL, Varrot A, Davies GJ, Rajan SS, Yang X, Thompson J, Anderson WF, Withers SG. Yip VL, et al. Among authors: withers sg. J Am Chem Soc. 2004 Jul 14;126(27):8354-5. doi: 10.1021/ja047632w. J Am Chem Soc. 2004. PMID: 15237973

2

Mechanisms of enzymatic glycoside hydrolysis.

McCarter JD, Withers SG. McCarter JD, et al. Among authors: withers sg. Curr Opin Struct Biol. 1994 Dec;4(6):885-92. doi: 10.1016/0959-440x(94)90271-2. Curr Opin Struct Biol. 1994. PMID: 7712292 Review.

3

Identification of the catalytic nucleophile of endoglucanase I from Fusarium oxysporum by mass spectrometry.

Mackenzie LF, Davies GJ, Schülein M, Withers SG. Mackenzie LF, et al. Among authors: withers sg. Biochemistry. 1997 May 13;36(19):5893-901. doi: 10.1021/bi962962h. Biochemistry. 1997. PMID: 9153431

4

Snapshots along an enzymatic reaction coordinate: analysis of a retaining beta-glycoside hydrolase.

Davies GJ, Mackenzie L, Varrot A, Dauter M, Brzozowski AM, Schülein M, Withers SG. Davies GJ, et al. Among authors: withers sg. Biochemistry. 1998 Aug 25;37(34):11707-13. doi: 10.1021/bi981315i. Biochemistry. 1998. PMID: 9718293

5

Crystal structure of the family 7 endoglucanase I (Cel7B) from Humicola insolens at 2.2 A resolution and identification of the catalytic nucleophile by trapping of the covalent glycosyl-enzyme intermediate.

MacKenzie LF, Sulzenbacher G, Divne C, Jones TA, Wöldike HF, Schülein M, Withers SG, Davies GJ. MacKenzie LF, et al. Among authors: withers sg. Biochem J. 1998 Oct 15;335 ( Pt 2)(Pt 2):409-16. doi: 10.1042/bj3350409. Biochem J. 1998. PMID: 9761741 Free PMC article.

6

The crystal structure of a 2-fluorocellotriosyl complex of the Streptomyces lividans endoglucanase CelB2 at 1.2 A resolution.

Sulzenbacher G, Mackenzie LF, Wilson KS, Withers SG, Dupont C, Davies GJ. Sulzenbacher G, et al. Among authors: withers sg. Biochemistry. 1999 Apr 13;38(15):4826-33. doi: 10.1021/bi982648i. Biochemistry. 1999. PMID: 10200171

7

Glycosidase mechanisms: anatomy of a finely tuned catalyst.

Zechel DL, Withers SG. Zechel DL, et al. Among authors: withers sg. Acc Chem Res. 2000 Jan;33(1):11-8. doi: 10.1021/ar970172+. Acc Chem Res. 2000. PMID: 10639071

8

Glycosidase mechanisms.

Rye CS, Withers SG. Rye CS, et al. Among authors: withers sg. Curr Opin Chem Biol. 2000 Oct;4(5):573-80. doi: 10.1016/s1367-5931(00)00135-6. Curr Opin Chem Biol. 2000. PMID: 11006547 Review.

9

Enzymatic synthesis of carbon-fluorine bonds.

Zechel DL, Reid SP, Nashiru O, Mayer C, Stoll D, Jakeman DL, Warren RA, Withers SG. Zechel DL, et al. Among authors: withers sg. J Am Chem Soc. 2001 May 9;123(18):4350-1. doi: 10.1021/ja005855q. J Am Chem Soc. 2001. PMID: 11457208 No abstract available.

10

Catalysis by hen egg-white lysozyme proceeds via a covalent intermediate.

Vocadlo DJ, Davies GJ, Laine R, Withers SG. Vocadlo DJ, et al. Among authors: withers sg. Nature. 2001 Aug 23;412(6849):835-8. doi: 10.1038/35090602. Nature. 2001. PMID: 11518970 Free article.

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