Sondek J - Search Results

1

PH domain of ELMO functions in trans to regulate Rac activation via Dock180.

Lu M, Kinchen JM, Rossman KL, Grimsley C, deBakker C, Brugnera E, Tosello-Trampont AC, Haney LB, Klingele D, Sondek J, Hengartner MO, Ravichandran KS. Lu M, et al. Among authors: sondek j. Nat Struct Mol Biol. 2004 Aug;11(8):756-62. doi: 10.1038/nsmb800. Epub 2004 Jul 11. Nat Struct Mol Biol. 2004. PMID: 15247908

2

Phagocytosis of apoptotic cells is regulated by a UNC-73/TRIO-MIG-2/RhoG signaling module and armadillo repeats of CED-12/ELMO.

deBakker CD, Haney LB, Kinchen JM, Grimsley C, Lu M, Klingele D, Hsu PK, Chou BK, Cheng LC, Blangy A, Sondek J, Hengartner MO, Wu YC, Ravichandran KS. deBakker CD, et al. Among authors: sondek j. Curr Biol. 2004 Dec 29;14(24):2208-16. doi: 10.1016/j.cub.2004.12.029. Curr Biol. 2004. PMID: 15620647 Free article.

3

A Steric-inhibition model for regulation of nucleotide exchange via the Dock180 family of GEFs.

Lu M, Kinchen JM, Rossman KL, Grimsley C, Hall M, Sondek J, Hengartner MO, Yajnik V, Ravichandran KS. Lu M, et al. Among authors: sondek j. Curr Biol. 2005 Feb 22;15(4):371-7. doi: 10.1016/j.cub.2005.01.050. Curr Biol. 2005. PMID: 15723800 Free article.

4

Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.

Snyder JT, Worthylake DK, Rossman KL, Betts L, Pruitt WM, Siderovski DP, Der CJ, Sondek J. Snyder JT, et al. Among authors: sondek j. Nat Struct Biol. 2002 Jun;9(6):468-75. doi: 10.1038/nsb796. Nat Struct Biol. 2002. PMID: 12006984

5

RhoGEF specificity mutants implicate RhoA as a target for Dbs transforming activity.

Cheng L, Rossman KL, Mahon GM, Worthylake DK, Korus M, Sondek J, Whitehead IP. Cheng L, et al. Among authors: sondek j. Mol Cell Biol. 2002 Oct;22(19):6895-905. doi: 10.1128/MCB.22.19.6895-6905.2002. Mol Cell Biol. 2002. PMID: 12215546 Free PMC article.

6

GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors.

Rossman KL, Der CJ, Sondek J. Rossman KL, et al. Among authors: sondek j. Nat Rev Mol Cell Biol. 2005 Feb;6(2):167-80. doi: 10.1038/nrm1587. Nat Rev Mol Cell Biol. 2005. PMID: 15688002 Review.

7

Larger than Dbl: new structural insights into RhoA activation.

Rossman KL, Sondek J. Rossman KL, et al. Among authors: sondek j. Trends Biochem Sci. 2005 Apr;30(4):163-5. doi: 10.1016/j.tibs.2005.02.002. Trends Biochem Sci. 2005. PMID: 15817389 Review.

8

Release of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression.

Mitin N, Betts L, Yohe ME, Der CJ, Sondek J, Rossman KL. Mitin N, et al. Among authors: sondek j. Nat Struct Mol Biol. 2007 Sep;14(9):814-23. doi: 10.1038/nsmb1290. Epub 2007 Aug 19. Nat Struct Mol Biol. 2007. PMID: 17704816 Free PMC article.

9

Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1.

Worthylake DK, Rossman KL, Sondek J. Worthylake DK, et al. Among authors: sondek j. Nature. 2000 Dec 7;408(6813):682-8. doi: 10.1038/35047014. Nature. 2000. PMID: 11130063

10

Molecular basis for Rac1 recognition by guanine nucleotide exchange factors.

Karnoub AE, Worthylake DK, Rossman KL, Pruitt WM, Campbell SL, Sondek J, Der CJ. Karnoub AE, et al. Among authors: sondek j. Nat Struct Biol. 2001 Dec;8(12):1037-41. doi: 10.1038/nsb719. Nat Struct Biol. 2001. PMID: 11685227

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