Wiesmann C - Search Results

1

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling.

Wertz IE, O'Rourke KM, Zhou H, Eby M, Aravind L, Seshagiri S, Wu P, Wiesmann C, Baker R, Boone DL, Ma A, Koonin EV, Dixit VM. Wertz IE, et al. Among authors: wiesmann c. Nature. 2004 Aug 5;430(7000):694-9. doi: 10.1038/nature02794. Epub 2004 Jul 18. Nature. 2004. PMID: 15258597

2

The crystal structure of murine coronin-1: a regulator of actin cytoskeletal dynamics in lymphocytes.

Appleton BA, Wu P, Wiesmann C. Appleton BA, et al. Among authors: wiesmann c. Structure. 2006 Jan;14(1):87-96. doi: 10.1016/j.str.2005.09.013. Structure. 2006. PMID: 16407068 Free article.

3

Structural and functional analysis of the ligand specificity of the HtrA2/Omi PDZ domain.

Zhang Y, Appleton BA, Wu P, Wiesmann C, Sidhu SS. Zhang Y, et al. Among authors: wiesmann c. Protein Sci. 2007 Aug;16(8):1738-50. doi: 10.1110/ps.072833207. Protein Sci. 2007. PMID: 17656586 Free PMC article.

4

Comparative structural analysis of the Erbin PDZ domain and the first PDZ domain of ZO-1. Insights into determinants of PDZ domain specificity.

Appleton BA, Zhang Y, Wu P, Yin JP, Hunziker W, Skelton NJ, Sidhu SS, Wiesmann C. Appleton BA, et al. Among authors: wiesmann c. J Biol Chem. 2006 Aug 4;281(31):22312-22320. doi: 10.1074/jbc.M602901200. Epub 2006 May 31. J Biol Chem. 2006. PMID: 16737969 Free article.

5

Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice.

Qing J, Du X, Chen Y, Chan P, Li H, Wu P, Marsters S, Stawicki S, Tien J, Totpal K, Ross S, Stinson S, Dornan D, French D, Wang QR, Stephan JP, Wu Y, Wiesmann C, Ashkenazi A. Qing J, et al. Among authors: wiesmann c. J Clin Invest. 2009 May;119(5):1216-29. doi: 10.1172/JCI38017. Epub 2009 Apr 20. J Clin Invest. 2009. PMID: 19381019 Free PMC article.

6

Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor.

Wiesmann C, Ultsch MH, Bass SH, de Vos AM. Wiesmann C, et al. Nature. 1999 Sep 9;401(6749):184-8. doi: 10.1038/43705. Nature. 1999. PMID: 10490030

7

Structure-function studies of two synthetic anti-vascular endothelial growth factor Fabs and comparison with the Avastin Fab.

Fuh G, Wu P, Liang WC, Ultsch M, Lee CV, Moffat B, Wiesmann C. Fuh G, et al. Among authors: wiesmann c. J Biol Chem. 2006 Mar 10;281(10):6625-31. doi: 10.1074/jbc.M507783200. Epub 2005 Dec 22. J Biol Chem. 2006. PMID: 16373345 Free article.

8

Comprehensive analysis of the factors contributing to the stability and solubility of autonomous human VH domains.

Barthelemy PA, Raab H, Appleton BA, Bond CJ, Wu P, Wiesmann C, Sidhu SS. Barthelemy PA, et al. Among authors: wiesmann c. J Biol Chem. 2008 Feb 8;283(6):3639-3654. doi: 10.1074/jbc.M708536200. Epub 2007 Nov 28. J Biol Chem. 2008. PMID: 18045863 Free article.

9

Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven cancers.

Hatzivassiliou G, Haling JR, Chen H, Song K, Price S, Heald R, Hewitt JF, Zak M, Peck A, Orr C, Merchant M, Hoeflich KP, Chan J, Luoh SM, Anderson DJ, Ludlam MJ, Wiesmann C, Ultsch M, Friedman LS, Malek S, Belvin M. Hatzivassiliou G, et al. Among authors: wiesmann c. Nature. 2013 Sep 12;501(7466):232-6. doi: 10.1038/nature12441. Epub 2013 Aug 11. Nature. 2013. PMID: 23934108

10

Inhibiting alternative pathway complement activation by targeting the factor D exosite.

Katschke KJ Jr, Wu P, Ganesan R, Kelley RF, Mathieu MA, Hass PE, Murray J, Kirchhofer D, Wiesmann C, van Lookeren Campagne M. Katschke KJ Jr, et al. Among authors: wiesmann c. J Biol Chem. 2012 Apr 13;287(16):12886-92. doi: 10.1074/jbc.M112.345082. Epub 2012 Feb 23. J Biol Chem. 2012. PMID: 22362762 Free PMC article.

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