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Page 1
Diaminopyrimidine and diaminopyridine 5-HT7 ligands.
Denhart DJ, Purandare AV, Catt JD, King HD, Gao A, Deskus JA, Poss MA, Stark AD, Torrente JR, Johnson G, Mattson RJ. Denhart DJ, et al. Among authors: deskus ja. Bioorg Med Chem Lett. 2004 Aug 16;14(16):4249-52. doi: 10.1016/j.bmcl.2004.06.007. Bioorg Med Chem Lett. 2004. PMID: 15261280
Aminotriazine 5-HT7 antagonists.
Mattson RJ, Denhart DJ, Catt JD, Dee MF, Deskus JA, Ditta JL, Epperson J, Dalton King H, Gao A, Poss MA, Purandare A, Tortolani D, Zhao Y, Yang H, Yeola S, Palmer J, Torrente J, Stark A, Johnson G. Mattson RJ, et al. Among authors: deskus ja. Bioorg Med Chem Lett. 2004 Aug 16;14(16):4245-8. doi: 10.1016/j.bmcl.2004.06.008. Bioorg Med Chem Lett. 2004. PMID: 15261279
Conformationally restricted homotryptamines 3. Indole tetrahydropyridines and cyclohexenylamines as selective serotonin reuptake inhibitors.
Deskus JA, Epperson JR, Sloan CP, Cipollina JA, Dextraze P, Qian-Cutrone J, Gao Q, Ma B, Beno BR, Mattson GK, Molski TF, Krause RG, Taber MT, Lodge NJ, Mattson RJ. Deskus JA, et al. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3099-104. doi: 10.1016/j.bmcl.2007.03.040. Epub 2007 Mar 16. Bioorg Med Chem Lett. 2007. PMID: 17391962
Conformationally restricted homotryptamines. Part 5: 3-(trans-2-aminomethylcyclopentyl)indoles as potent selective serotonin reuptake inhibitors.
Denhart DJ, Deskus JA, Ditta JL, Gao Q, Dalton King H, Kozlowski ES, Meng Z, LaPaglia MA, Mattson GK, Molski TF, Taber MT, Lodge NJ, Mattson RJ, Macor JE. Denhart DJ, et al. Among authors: deskus ja. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4031-3. doi: 10.1016/j.bmcl.2009.06.026. Epub 2009 Jun 13. Bioorg Med Chem Lett. 2009. PMID: 19560923
Heterocyclic aminopyrrolidine derivatives as melatoninergic agents.
Sun LQ, Chen J, Mattson RJ, Epperson JR, Deskus JA, Li WS, Takaki K, Hodges DB, Iben L, Mahle CD, Ortiz A, Molstad D, Ryan E, Yeleswaram K, Xu C, Luo G. Sun LQ, et al. Among authors: deskus ja. Bioorg Med Chem Lett. 2003 Dec 15;13(24):4381-4. doi: 10.1016/j.bmcl.2003.09.030. Bioorg Med Chem Lett. 2003. PMID: 14643330
Chronobiotic activity of N-[2-(2,7-dimethoxyfluoren-9-yl)ethyl]-propanamide. Synthesis and melatonergic pharmacology of fluoren-9-ylethyl amides.
Epperson JR, Bruce MA, Catt JD, Deskus JA, Hodges DB, Karageorge GN, Keavy DJ, Mahle CD, Mattson RJ, Ortiz AA, Parker MF, Takaki KS, Watson BT, Joseph P Yevich. Epperson JR, et al. Among authors: deskus ja. Bioorg Med Chem. 2004 Sep 1;12(17):4601-11. doi: 10.1016/j.bmc.2004.07.002. Bioorg Med Chem. 2004. PMID: 15358287
Conformationally restricted homotryptamines. Part 4: Heterocyclic and naphthyl analogs of a potent selective serotonin reuptake inhibitor.
Dalton King H, Denhart DJ, Deskus JA, Ditta JL, Epperson JR, Higgins MA, Kung JE, Marcin LR, Sloan CP, Mattson GK, Molski TF, Krause RG, Bertekap RL Jr, Lodge NJ, Mattson RJ, Macor JE. Dalton King H, et al. Among authors: deskus ja. Bioorg Med Chem Lett. 2007 Oct 15;17(20):5647-51. doi: 10.1016/j.bmcl.2007.07.083. Epub 2007 Aug 22. Bioorg Med Chem Lett. 2007. PMID: 17766113
In vitro intrinsic clearance-based optimization of N3-phenylpyrazinones as corticotropin-releasing factor-1 (CRF1) receptor antagonists.
Hartz RA, Ahuja VT, Rafalski M, Schmitz WD, Brenner AB, Denhart DJ, Ditta JL, Deskus JA, Yue EW, Arvanitis AG, Lelas S, Li YW, Molski TF, Wong H, Grace JE, Lentz KA, Li J, Lodge NJ, Zaczek R, Combs AP, Olson RE, Mattson RJ, Bronson JJ, Macor JE. Hartz RA, et al. Among authors: deskus ja. J Med Chem. 2009 Jul 23;52(14):4161-72. doi: 10.1021/jm900302q. J Med Chem. 2009. PMID: 19552436
20 results