Wong BK - Search Results

1

Comparative disposition of [14C]ertapenem, a novel carbapenem antibiotic, in rat, monkey and man.

Wong BK, Sahly Y, Mistry G, Waldman S, Musson D, Majumdar A, Xu X, Yu S, Lin JH, Singh R, Holland S. Wong BK, et al. Xenobiotica. 2004 Apr;34(4):379-89. doi: 10.1080/00498250410001670643. Xenobiotica. 2004. PMID: 15268982 Clinical Trial.

2

Column-switching high-pressure liquid chromatographic method for the determination of a new carbapenem antibiotic, L-739,428, in rat and monkey plasma.

Wong BK, Bruhin PJ, Lin JH. Wong BK, et al. J Chromatogr B Biomed Appl. 1994 Apr 22;655(1):158-62. doi: 10.1016/s0378-4347(94)80130-4. J Chromatogr B Biomed Appl. 1994. PMID: 8061826

3

Dose-dependent plasma clearance of MK-826, a carbapenem antibiotic, arising from concentration-dependent plasma protein binding in rats and monkeys.

Wong BK, Bruhin PJ, Lin JH. Wong BK, et al. J Pharm Sci. 1999 Feb;88(2):277-80. doi: 10.1021/js980232k. J Pharm Sci. 1999. PMID: 9950650

4

Complexities of glucuronidation affecting in vitro in vivo extrapolation.

Lin JH, Wong BK. Lin JH, et al. Among authors: wong bk. Curr Drug Metab. 2002 Dec;3(6):623-46. doi: 10.2174/1389200023336992. Curr Drug Metab. 2002. PMID: 12369890 Review.

5

Pharmacokinetics and metabolism of a RAS farnesyl transferase inhibitor in rats and dogs: in vitro-in vivo correlation.

Singh R, Chen IW, Jin L, Silva MV, Arison BH, Lin JH, Wong BK. Singh R, et al. Among authors: wong bk. Drug Metab Dispos. 2001 Dec;29(12):1578-87. Drug Metab Dispos. 2001. PMID: 11717177

6

Nonlinear dorzolamide pharmacokinetics in rats: concentration-dependent erythrocyte distribution and drug-metabolite displacement interaction.

Wong BK, Bruhin PJ, Barrish A, Lin JH. Wong BK, et al. Drug Metab Dispos. 1996 Jun;24(6):659-63. Drug Metab Dispos. 1996. PMID: 8781782

7

Dose-dependent pharmacokinetics of L-693,612, a carbonic anhydrase inhibitor, following oral administration in rats.

Wong BK, Bruhin PJ, Lin JH. Wong BK, et al. Pharm Res. 1994 Mar;11(3):438-41. doi: 10.1023/a:1018977423947. Pharm Res. 1994. PMID: 8008713

8

PSA-specific and non-PSA-specific conversion of a PSA-targeted peptide conjugate of doxorubicin to its active metabolites.

Wong BK, DeFeo-Jones D, Jones RE, Garsky VM, Feng DM, Oliff A, Chiba M, Ellis JD, Lin JH. Wong BK, et al. Drug Metab Dispos. 2001 Mar;29(3):313-8. Drug Metab Dispos. 2001. PMID: 11181501

9

Metabolic activation of a pyrazinone-containing thrombin inhibitor. Evidence for novel biotransformation involving pyrazinone ring oxidation, rearrangement, and covalent binding to proteins.

Singh R, Silva Elipe MV, Pearson PG, Arison BH, Wong BK, White R, Yu X, Burgey CS, Lin JH, Baillie TA. Singh R, et al. Among authors: wong bk. Chem Res Toxicol. 2003 Feb;16(2):198-207. doi: 10.1021/tx025635l. Chem Res Toxicol. 2003. PMID: 12588191

10

Enzyme kinetics of cytochrome P450-mediated reactions.

Shou M, Lin Y, Lu P, Tang C, Mei Q, Cui D, Tang W, Ngui JS, Lin CC, Singh R, Wong BK, Yergey JA, Lin JH, Pearson PG, Baillie TA, Rodrigues AD, Rushmore TH. Shou M, et al. Among authors: wong bk. Curr Drug Metab. 2001 Mar;2(1):17-36. doi: 10.2174/1389200013338784. Curr Drug Metab. 2001. PMID: 11465149 Review.

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