Ortega S - Search Results

1

Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6.

Malumbres M, Sotillo R, Santamaría D, Galán J, Cerezo A, Ortega S, Dubus P, Barbacid M. Malumbres M, et al. Among authors: ortega s. Cell. 2004 Aug 20;118(4):493-504. doi: 10.1016/j.cell.2004.08.002. Cell. 2004. PMID: 15315761 Free article.

2

Limited overlapping roles of P15(INK4b) and P18(INK4c) cell cycle inhibitors in proliferation and tumorigenesis.

Latres E, Malumbres M, Sotillo R, Martín J, Ortega S, Martín-Caballero J, Flores JM, Cordón-Cardo C, Barbacid M. Latres E, et al. Among authors: ortega s. EMBO J. 2000 Jul 3;19(13):3496-506. doi: 10.1093/emboj/19.13.3496. EMBO J. 2000. PMID: 10880462 Free PMC article.

3

Genetic analysis of mammalian cyclin-dependent kinases and their inhibitors.

Malumbres M, Ortega S, Barbacid M. Malumbres M, et al. Among authors: ortega s. Biol Chem. 2000 Sep-Oct;381(9-10):827-38. doi: 10.1515/BC.2000.105. Biol Chem. 2000. PMID: 11076015 Review.

4

Invasive melanoma in Cdk4-targeted mice.

Sotillo R, García JF, Ortega S, Martin J, Dubus P, Barbacid M, Malumbres M. Sotillo R, et al. Among authors: ortega s. Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):13312-7. doi: 10.1073/pnas.241338598. Epub 2001 Oct 23. Proc Natl Acad Sci U S A. 2001. PMID: 11606789 Free PMC article.

5

Wide spectrum of tumors in knock-in mice carrying a Cdk4 protein insensitive to INK4 inhibitors.

Sotillo R, Dubus P, Martín J, de la Cueva E, Ortega S, Malumbres M, Barbacid M. Sotillo R, et al. Among authors: ortega s. EMBO J. 2001 Dec 3;20(23):6637-47. doi: 10.1093/emboj/20.23.6637. EMBO J. 2001. PMID: 11726500 Free PMC article.

6

Cyclin D-dependent kinases, INK4 inhibitors and cancer.

Ortega S, Malumbres M, Barbacid M. Ortega S, et al. Biochim Biophys Acta. 2002 Mar 14;1602(1):73-87. doi: 10.1016/s0304-419x(02)00037-9. Biochim Biophys Acta. 2002. PMID: 11960696 Review.

7

Driving the cell cycle to cancer.

Malumbres M, Hunt SL, Sotillo R, Martín J, Odajima J, Martín A, Dubus P, Ortega S, Barbacid M. Malumbres M, et al. Among authors: ortega s. Adv Exp Med Biol. 2003;532:1-11. doi: 10.1007/978-1-4615-0081-0_1. Adv Exp Med Biol. 2003. PMID: 12908544 Review.

8

Genetic rescue of Cdk4 null mice restores pancreatic beta-cell proliferation but not homeostatic cell number.

Martín J, Hunt SL, Dubus P, Sotillo R, Néhmé-Pélluard F, Magnuson MA, Parlow AF, Malumbres M, Ortega S, Barbacid M. Martín J, et al. Among authors: ortega s. Oncogene. 2003 Aug 14;22(34):5261-9. doi: 10.1038/sj.onc.1206506. Oncogene. 2003. PMID: 12917627

9

Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice.

Ortega S, Prieto I, Odajima J, Martín A, Dubus P, Sotillo R, Barbero JL, Malumbres M, Barbacid M. Ortega S, et al. Nat Genet. 2003 Sep;35(1):25-31. doi: 10.1038/ng1232. Epub 2003 Aug 17. Nat Genet. 2003. PMID: 12923533

10

Cdk2 is dispensable for cell cycle inhibition and tumor suppression mediated by p27(Kip1) and p21(Cip1).

Martín A, Odajima J, Hunt SL, Dubus P, Ortega S, Malumbres M, Barbacid M. Martín A, et al. Among authors: ortega s. Cancer Cell. 2005 Jun;7(6):591-8. doi: 10.1016/j.ccr.2005.05.006. Cancer Cell. 2005. PMID: 15950907 Free article.

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