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Myosin phosphatase: structure, regulation and function.
Ito M, Nakano T, Erdodi F, Hartshorne DJ. Ito M, et al. Mol Cell Biochem. 2004 Apr;259(1-2):197-209. doi: 10.1023/b:mcbi.0000021373.14288.00. Mol Cell Biochem. 2004. PMID: 15124925 Review.
The targeted disruption of the MYPT1 gene results in embryonic lethality.
Okamoto R, Ito M, Suzuki N, Kongo M, Moriki N, Saito H, Tsumura H, Imanaka-Yoshida K, Kimura K, Mizoguchi A, Hartshorne DJ, Nakano T. Okamoto R, et al. Among authors: ito m. Transgenic Res. 2005 Jun;14(3):337-40. doi: 10.1007/s11248-005-3453-3. Transgenic Res. 2005. PMID: 16145842
Characterization and function of MYPT2, a target subunit of myosin phosphatase in heart.
Okamoto R, Kato T, Mizoguchi A, Takahashi N, Nakakuki T, Mizutani H, Isaka N, Imanaka-Yoshida K, Kaibuchi K, Lu Z, Mabuchi K, Tao T, Hartshorne DJ, Nakano T, Ito M. Okamoto R, et al. Among authors: ito m. Cell Signal. 2006 Sep;18(9):1408-16. doi: 10.1016/j.cellsig.2005.11.001. Epub 2006 Jan 23. Cell Signal. 2006. PMID: 16431080
Urocortin-induced decrease in Ca2+ sensitivity of contraction in mouse tail arteries is attributable to cAMP-dependent dephosphorylation of MYPT1 and activation of myosin light chain phosphatase.
Lubomirov LT, Reimann K, Metzler D, Hasse V, Stehle R, Ito M, Hartshorne DJ, Gagov H, Pfitzer G, Schubert R. Lubomirov LT, et al. Among authors: ito m. Circ Res. 2006 May 12;98(9):1159-67. doi: 10.1161/01.RES.0000219904.43852.3e. Epub 2006 Mar 30. Circ Res. 2006. PMID: 16574904
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