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Page 1
Chronobiotic activity of N-[2-(2,7-dimethoxyfluoren-9-yl)ethyl]-propanamide. Synthesis and melatonergic pharmacology of fluoren-9-ylethyl amides.
Epperson JR, Bruce MA, Catt JD, Deskus JA, Hodges DB, Karageorge GN, Keavy DJ, Mahle CD, Mattson RJ, Ortiz AA, Parker MF, Takaki KS, Watson BT, Joseph P Yevich. Epperson JR, et al. Among authors: ortiz aa. Bioorg Med Chem. 2004 Sep 1;12(17):4601-11. doi: 10.1016/j.bmc.2004.07.002. Bioorg Med Chem. 2004. PMID: 15358287
Heterocyclic aminopyrrolidine derivatives as melatoninergic agents.
Sun LQ, Chen J, Mattson RJ, Epperson JR, Deskus JA, Li WS, Takaki K, Hodges DB, Iben L, Mahle CD, Ortiz A, Molstad D, Ryan E, Yeleswaram K, Xu C, Luo G. Sun LQ, et al. Bioorg Med Chem Lett. 2003 Dec 15;13(24):4381-4. doi: 10.1016/j.bmcl.2003.09.030. Bioorg Med Chem Lett. 2003. PMID: 14643330
Dihydropyridine neuropeptide Y Y(1) receptor antagonists.
Poindexter GS, Bruce MA, LeBoulluec KL, Monkovic I, Martin SW, Parker EM, Iben LG, McGovern RT, Ortiz AA, Stanley JA, Mattson GK, Kozlowski M, Arcuri M, Antal-Zimanyi I. Poindexter GS, et al. Among authors: ortiz aa. Bioorg Med Chem Lett. 2002 Feb 11;12(3):379-82. doi: 10.1016/s0960-894x(01)00761-2. Bioorg Med Chem Lett. 2002. PMID: 11814801
Pharmacological characterization and appetite suppressive properties of BMS-193885, a novel and selective neuropeptide Y(1) receptor antagonist.
Antal-Zimanyi I, Bruce MA, Leboulluec KL, Iben LG, Mattson GK, McGovern RT, Hogan JB, Leahy CL, Flowers SC, Stanley JA, Ortiz AA, Poindexter GS. Antal-Zimanyi I, et al. Among authors: ortiz aa. Eur J Pharmacol. 2008 Aug 20;590(1-3):224-32. doi: 10.1016/j.ejphar.2008.06.032. Epub 2008 Jun 12. Eur J Pharmacol. 2008. PMID: 18573246
3-[(5-Chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl ]-1,3,4-oxadiazol-2(3H)-one, BMS-191011: opener of large-conductance Ca(2+)-activated potassium (maxi-K) channels, identification, solubility, and SAR.
Romine JL, Martin SW, Meanwell NA, Gribkoff VK, Boissard CG, Dworetzky SI, Natale J, Moon S, Ortiz A, Yeleswaram S, Pajor L, Gao Q, Starrett JE Jr. Romine JL, et al. J Med Chem. 2007 Feb 8;50(3):528-42. doi: 10.1021/jm061006n. J Med Chem. 2007. PMID: 17266205
Constrained analogs of CB-1 antagonists: 1,5,6,7-Tetrahydro-4H-pyrrolo[3,2-c]pyridine-4-one derivatives.
Smith RA, Fathi Z, Brown SE, Choi S, Fan J, Jenkins S, Kluender HC, Konkar A, Lavoie R, Mays R, Natoli J, O'Connor SJ, Ortiz AA, Podlogar B, Taing C, Tomlinson S, Tritto T, Zhang Z. Smith RA, et al. Among authors: ortiz aa. Bioorg Med Chem Lett. 2007 Feb 1;17(3):673-8. doi: 10.1016/j.bmcl.2006.10.095. Epub 2006 Nov 2. Bioorg Med Chem Lett. 2007. PMID: 17107792
35 results