Bertino JR - Search Results

1

Protection of hematopoietic stem cells from pemetrexed toxicity by retroviral gene transfer with a mutant dihydrofolate reductase-mutant thymidylate synthase fusion gene.

Capiaux GM, Budak-Alpdogan T, Alpdogan O, Bornmann W, Takebe N, Banerjee D, Maley F, Bertino JR. Capiaux GM, et al. Among authors: bertino jr. Cancer Gene Ther. 2004 Dec;11(12):767-73. doi: 10.1038/sj.cgt.7700683. Cancer Gene Ther. 2004. PMID: 15359285

2

Methotrexate selection of long-term culture initiating cells following transduction of CD34(+) cells with a retrovirus containing a mutated human dihydrofolate reductase gene.

Takebe N, Xu LC, MacKenzie KL, Bertino JR, Moore MA. Takebe N, et al. Among authors: bertino jr. Cancer Gene Ther. 2002 Mar;9(3):308-20. doi: 10.1038/sj.cgt.7700443. Cancer Gene Ther. 2002. PMID: 11896448

3

Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase.

Banerjee D, Mayer-Kuckuk P, Capiaux G, Budak-Alpdogan T, Gorlick R, Bertino JR. Banerjee D, et al. Among authors: bertino jr. Biochim Biophys Acta. 2002 Jul 18;1587(2-3):164-73. doi: 10.1016/s0925-4439(02)00079-0. Biochim Biophys Acta. 2002. PMID: 12084458 Free article. Review.

4

Retroviral transduction of a mutant dihydrofolate reductase-thymidylate synthase fusion gene into murine marrow cells confers resistance to both methotrexate and 5-fluorouracil.

Capiaux GM, Budak-Alpdogan T, Takebe N, Mayer-Kuckuk P, Banerjee D, Maley F, Bertino JR. Capiaux GM, et al. Among authors: bertino jr. Hum Gene Ther. 2003 Mar 20;14(5):435-46. doi: 10.1089/104303403321467207. Hum Gene Ther. 2003. PMID: 12691609

5

p14ARF expression increases dihydrofolate reductase degradation and paradoxically results in resistance to folate antagonists in cells with nonfunctional p53.

Magro PG, Russo AJ, Li WW, Banerjee D, Bertino JR. Magro PG, et al. Among authors: bertino jr. Cancer Res. 2004 Jun 15;64(12):4338-45. doi: 10.1158/0008-5472.CAN-03-1045. Cancer Res. 2004. PMID: 15205349

6

Methotrexate and cytarabine inhibit progression of human lymphoma in NOD/SCID mice carrying a mutant dihydrofolate reductase and cytidine deaminase fusion gene.

Budak-Alpdogan T, Alpdogan O, Banerjee D, Wang E, Moore MA, Bertino JR. Budak-Alpdogan T, et al. Among authors: bertino jr. Mol Ther. 2004 Sep;10(3):574-84. doi: 10.1016/j.ymthe.2004.06.115. Mol Ther. 2004. PMID: 15336657 Free article.

7

Hematopoietic stem cell gene therapy with drug resistance genes: an update.

Budak-Alpdogan T, Banerjee D, Bertino JR. Budak-Alpdogan T, et al. Among authors: bertino jr. Cancer Gene Ther. 2005 Nov;12(11):849-63. doi: 10.1038/sj.cgt.7700866. Cancer Gene Ther. 2005. PMID: 16037821 Review.

8

Long-term protection of recipient mice from lethal doses of methotrexate by marrow infected with a double-copy vector retrovirus containing a mutant dihydrofolate reductase.

Zhao SC, Li MX, Banerjee D, Schweitzer BI, Mineishi S, Gilboa E, Bertino JR. Zhao SC, et al. Among authors: bertino jr. Cancer Gene Ther. 1994 Mar;1(1):27-33. Cancer Gene Ther. 1994. PMID: 7621235

9

Transfection of a nonactive site mutant murine DHFR cDNA (the tryptophan 15 mutant) into Chinese hamster ovary and mouse marrow progenitor cells imparts MTX resistance in vitro.

Banerjee D, Zhao SC, Tong Y, Steinherz J, Gritsman K, Bertino JR. Banerjee D, et al. Among authors: bertino jr. Cancer Gene Ther. 1994 Sep;1(3):181-4. Cancer Gene Ther. 1994. PMID: 7621249

10

Post-transplant methotrexate administration leads to improved curability of mice bearing a mammary tumor transplanted with marrow transduced with a mutant human dihydrofolate reductase cDNA.

Zhao SC, Banerjee D, Mineishi S, Bertino JR. Zhao SC, et al. Among authors: bertino jr. Hum Gene Ther. 1997 May 20;8(8):903-9. doi: 10.1089/hum.1997.8.8-903. Hum Gene Ther. 1997. PMID: 9195212

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