Schaefer VG - Search Results

1

Novel isoxazole carboxamides as growth hormone secretagogue receptor (GHS-R) antagonists.

Liu B, Liu G, Xin Z, Serby MD, Zhao H, Schaefer VG, Falls HD, Kaszubska W, Collins CA, Sham HL. Liu B, et al. Among authors: schaefer vg. Bioorg Med Chem Lett. 2004 Oct 18;14(20):5223-6. doi: 10.1016/j.bmcl.2004.06.060. Bioorg Med Chem Lett. 2004. PMID: 15380232

2

2,4-diaminopyrimidine derivatives as potent growth hormone secretagogue receptor antagonists.

Serby MD, Zhao H, Szczepankiewicz BG, Kosogof C, Xin Z, Liu B, Liu M, Nelson LT, Kaszubska W, Falls HD, Schaefer V, Bush EN, Shapiro R, Droz BA, Knourek-Segel VE, Fey TA, Brune ME, Beno DW, Turner TM, Collins CA, Jacobson PB, Sham HL, Liu G. Serby MD, et al. J Med Chem. 2006 Apr 20;49(8):2568-78. doi: 10.1021/jm0510934. J Med Chem. 2006. PMID: 16610800

3

Discovery of tetralin carboxamide growth hormone secretagogue receptor antagonists via scaffold manipulation.

Zhao H, Xin Z, Liu G, Schaefer VG, Falls HD, Kaszubska W, Collins CA, Sham HL. Zhao H, et al. Among authors: schaefer vg. J Med Chem. 2004 Dec 30;47(27):6655-7. doi: 10.1021/jm0491750. J Med Chem. 2004. PMID: 15615511

4

Synthesis and structure-activity relationships of isoxazole carboxamides as growth hormone secretagogue receptor antagonists.

Xin Z, Zhao H, Serby MD, Liu B, Schaefer VG, Falls DH, Kaszubska W, Colins CA, Sham HL, Liu G. Xin Z, et al. Among authors: schaefer vg. Bioorg Med Chem Lett. 2005 Feb 15;15(4):1201-4. doi: 10.1016/j.bmcl.2004.11.075. Bioorg Med Chem Lett. 2005. PMID: 15686942

5

Structure-activity relationship studies on tetralin carboxamide growth hormone secretagogue receptor antagonists.

Zhao H, Xin Z, Patel JR, Nelson LT, Liu B, Szczepankiewicz BG, Schaefer VG, Falls HD, Kaszubska W, Collins CA, Sham HL, Liu G. Zhao H, et al. Among authors: schaefer vg. Bioorg Med Chem Lett. 2005 Apr 1;15(7):1825-8. doi: 10.1016/j.bmcl.2005.02.026. Bioorg Med Chem Lett. 2005. PMID: 15780615

6

Optimization of 2,4-diaminopyrimidines as GHS-R antagonists: side chain exploration.

Liu B, Liu M, Xin Z, Zhao H, Serby MD, Kosogof C, Nelson LT, Szczepankiewicz BG, Kaszubska W, Schaefer VG, Falls HD, Lin CW, Collins CA, Sham HL, Liu G. Liu B, et al. Among authors: schaefer vg. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1864-8. doi: 10.1016/j.bmcl.2006.01.012. Epub 2006 Jan 25. Bioorg Med Chem Lett. 2006. PMID: 16442284

7

Characterization of ghrelin receptor activity in a rat pituitary cell line RC-4B/C.

Falls HD, Dayton BD, Fry DG, Ogiela CA, Schaefer VG, Brodjian S, Reilly RM, Collins CA, Kaszubska W. Falls HD, et al. Among authors: schaefer vg. J Mol Endocrinol. 2006 Aug;37(1):51-62. doi: 10.1677/jme.1.01943. J Mol Endocrinol. 2006. PMID: 16901923

8

Protein tyrosine phosphatase 1B negatively regulates leptin signaling in a hypothalamic cell line.

Kaszubska W, Falls HD, Schaefer VG, Haasch D, Frost L, Hessler P, Kroeger PE, White DW, Jirousek MR, Trevillyan JM. Kaszubska W, et al. Among authors: schaefer vg. Mol Cell Endocrinol. 2002 Sep 30;195(1-2):109-18. doi: 10.1016/s0303-7207(02)00178-8. Mol Cell Endocrinol. 2002. PMID: 12354677

9

Selective inhibition of ICAM-1 and E-selectin expression in human endothelial cells. 2. Aryl modifications of 4-(aryloxy)thieno[2,3-c]pyridines with fine-tuning at C-2 carbamides.

Zhu GD, Arendsen DL, Gunawardana IW, Boyd SA, Stewart AO, Fry DG, Cool BL, Kifle L, Schaefer V, Meuth J, Marsh KC, Kempf-Grote AJ, Kilgannon P, Gallatin WM, Okasinski GF. Zhu GD, et al. J Med Chem. 2001 Oct 11;44(21):3469-87. doi: 10.1021/jm0101702. J Med Chem. 2001. PMID: 11585452

10

Expression, purification, and characterization of human recombinant thrombopoietin in Chinese hamster ovary cells.

Kaszubska W, Zhang H, Patterson RL, Suhar TS, Uchic ME, Dickinson RW, Schaefer VG, Haasch D, Janis RS, DeVries PJ, Okasinski GF, Meuth JL. Kaszubska W, et al. Among authors: schaefer vg. Protein Expr Purif. 2000 Mar;18(2):213-20. doi: 10.1006/prep.1999.1190. Protein Expr Purif. 2000. PMID: 10686152

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