Zhao H - Search Results

1

Novel isoxazole carboxamides as growth hormone secretagogue receptor (GHS-R) antagonists.

Liu B, Liu G, Xin Z, Serby MD, Zhao H, Schaefer VG, Falls HD, Kaszubska W, Collins CA, Sham HL. Liu B, et al. Among authors: zhao h. Bioorg Med Chem Lett. 2004 Oct 18;14(20):5223-6. doi: 10.1016/j.bmcl.2004.06.060. Bioorg Med Chem Lett. 2004. PMID: 15380232

2

Fragment screening and assembly: a highly efficient approach to a selective and cell active protein tyrosine phosphatase 1B inhibitor.

Liu G, Xin Z, Pei Z, Hajduk PJ, Abad-Zapatero C, Hutchins CW, Zhao H, Lubben TH, Ballaron SJ, Haasch DL, Kaszubska W, Rondinone CM, Trevillyan JM, Jirousek MR. Liu G, et al. Among authors: zhao h. J Med Chem. 2003 Sep 25;46(20):4232-5. doi: 10.1021/jm034122o. J Med Chem. 2003. PMID: 13678400

3

Isoxazole carboxylic acids as protein tyrosine phosphatase 1B (PTP1B) inhibitors.

Zhao H, Liu G, Xin Z, Serby MD, Pei Z, Szczepankiewicz BG, Hajduk PJ, Abad-Zapatero C, Hutchins CW, Lubben TH, Ballaron SJ, Haasch DL, Kaszubska W, Rondinone CM, Trevillyan JM, Jirousek MR. Zhao H, et al. Bioorg Med Chem Lett. 2004 Nov 15;14(22):5543-6. doi: 10.1016/j.bmcl.2004.08.063. Bioorg Med Chem Lett. 2004. PMID: 15482920

4

Discovery of tetralin carboxamide growth hormone secretagogue receptor antagonists via scaffold manipulation.

Zhao H, Xin Z, Liu G, Schaefer VG, Falls HD, Kaszubska W, Collins CA, Sham HL. Zhao H, et al. J Med Chem. 2004 Dec 30;47(27):6655-7. doi: 10.1021/jm0491750. J Med Chem. 2004. PMID: 15615511

5

Synthesis and structure-activity relationships of isoxazole carboxamides as growth hormone secretagogue receptor antagonists.

Xin Z, Zhao H, Serby MD, Liu B, Schaefer VG, Falls DH, Kaszubska W, Colins CA, Sham HL, Liu G. Xin Z, et al. Among authors: zhao h. Bioorg Med Chem Lett. 2005 Feb 15;15(4):1201-4. doi: 10.1016/j.bmcl.2004.11.075. Bioorg Med Chem Lett. 2005. PMID: 15686942

6

Structure-activity relationship studies on tetralin carboxamide growth hormone secretagogue receptor antagonists.

Zhao H, Xin Z, Patel JR, Nelson LT, Liu B, Szczepankiewicz BG, Schaefer VG, Falls HD, Kaszubska W, Collins CA, Sham HL, Liu G. Zhao H, et al. Bioorg Med Chem Lett. 2005 Apr 1;15(7):1825-8. doi: 10.1016/j.bmcl.2005.02.026. Bioorg Med Chem Lett. 2005. PMID: 15780615

7

Optimization of 2,4-diaminopyrimidines as GHS-R antagonists: side chain exploration.

Liu B, Liu M, Xin Z, Zhao H, Serby MD, Kosogof C, Nelson LT, Szczepankiewicz BG, Kaszubska W, Schaefer VG, Falls HD, Lin CW, Collins CA, Sham HL, Liu G. Liu B, et al. Among authors: zhao h. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1864-8. doi: 10.1016/j.bmcl.2006.01.012. Epub 2006 Jan 25. Bioorg Med Chem Lett. 2006. PMID: 16442284

8

2,4-diaminopyrimidine derivatives as potent growth hormone secretagogue receptor antagonists.

Serby MD, Zhao H, Szczepankiewicz BG, Kosogof C, Xin Z, Liu B, Liu M, Nelson LT, Kaszubska W, Falls HD, Schaefer V, Bush EN, Shapiro R, Droz BA, Knourek-Segel VE, Fey TA, Brune ME, Beno DW, Turner TM, Collins CA, Jacobson PB, Sham HL, Liu G. Serby MD, et al. Among authors: zhao h. J Med Chem. 2006 Apr 20;49(8):2568-78. doi: 10.1021/jm0510934. J Med Chem. 2006. PMID: 16610800

9

Discovery of potent, highly selective, and orally bioavailable pyridine carboxamide c-Jun NH2-terminal kinase inhibitors.

Zhao H, Serby MD, Xin Z, Szczepankiewicz BG, Liu M, Kosogof C, Liu B, Nelson LT, Johnson EF, Wang S, Pederson T, Gum RJ, Clampit JE, Haasch DL, Abad-Zapatero C, Fry EH, Rondinone C, Trevillyan JM, Sham HL, Liu G. Zhao H, et al. J Med Chem. 2006 Jul 27;49(15):4455-8. doi: 10.1021/jm060465l. J Med Chem. 2006. PMID: 16854050

10

Discovery and pharmacological evaluation of growth hormone secretagogue receptor antagonists.

Xin Z, Serby MD, Zhao H, Kosogof C, Szczepankiewicz BG, Liu M, Liu B, Hutchins CW, Sarris KA, Hoff ED, Falls HD, Lin CW, Ogiela CA, Collins CA, Brune ME, Bush EN, Droz BA, Fey TA, Knourek-Segel VE, Shapiro R, Jacobson PB, Beno DW, Turner TM, Sham HL, Liu G. Xin Z, et al. Among authors: zhao h. J Med Chem. 2006 Jul 27;49(15):4459-69. doi: 10.1021/jm060461g. J Med Chem. 2006. PMID: 16854051

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