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Efficacy of PLD-118, a novel inhibitor of candida isoleucyl-tRNA synthetase, against experimental oropharyngeal and esophageal candidiasis caused by fluconazole-resistant C. albicans.
Petraitis V, Petraitiene R, Kelaher AM, Sarafandi AA, Sein T, Mickiene D, Bacher J, Groll AH, Walsh TJ. Petraitis V, et al. Among authors: sein t. Antimicrob Agents Chemother. 2004 Oct;48(10):3959-67. doi: 10.1128/AAC.48.10.3959-3967.2004. Antimicrob Agents Chemother. 2004. PMID: 15388459 Free PMC article.
Antifungal efficacy of caspofungin (MK-0991) in experimental pulmonary aspergillosis in persistently neutropenic rabbits: pharmacokinetics, drug disposition, and relationship to galactomannan antigenemia.
Petraitiene R, Petraitis V, Groll AH, Sein T, Schaufele RL, Francesconi A, Bacher J, Avila NA, Walsh TJ. Petraitiene R, et al. Among authors: sein t. Antimicrob Agents Chemother. 2002 Jan;46(1):12-23. doi: 10.1128/AAC.46.1.12-23.2002. Antimicrob Agents Chemother. 2002. PMID: 11751105 Free PMC article.
Comparative antifungal activities and plasma pharmacokinetics of micafungin (FK463) against disseminated candidiasis and invasive pulmonary aspergillosis in persistently neutropenic rabbits.
Petraitis V, Petraitiene R, Groll AH, Roussillon K, Hemmings M, Lyman CA, Sein T, Bacher J, Bekersky I, Walsh TJ. Petraitis V, et al. Among authors: sein t. Antimicrob Agents Chemother. 2002 Jun;46(6):1857-69. doi: 10.1128/AAC.46.6.1857-1869.2002. Antimicrob Agents Chemother. 2002. PMID: 12019101 Free PMC article.
Efficacy, plasma pharmacokinetics, and safety of icofungipen, an inhibitor of Candida isoleucyl-tRNA synthetase, in treatment of experimental disseminated candidiasis in persistently neutropenic rabbits.
Petraitiene R, Petraitis V, Kelaher AM, Sarafandi AA, Mickiene D, Groll AH, Sein T, Bacher J, Walsh TJ. Petraitiene R, et al. Among authors: sein t. Antimicrob Agents Chemother. 2005 May;49(5):2084-92. doi: 10.1128/AAC.49.5.2084-2092.2005. Antimicrob Agents Chemother. 2005. PMID: 15855534 Free PMC article.
Multidimensional volumetric imaging of pulmonary infiltrates for measuring therapeutic response to antifungal therapy in experimental invasive pulmonary aspergillosis.
Petraitis V, Petraitiene R, Solomon J, Kelaher AM, Murray HA, Mya-San C, Bhandary AK, Sein T, Avila NA, Basevicius A, Bacher J, Walsh TJ. Petraitis V, et al. Among authors: sein t. Antimicrob Agents Chemother. 2006 Apr;50(4):1510-7. doi: 10.1128/AAC.50.4.1510-1517.2006. Antimicrob Agents Chemother. 2006. PMID: 16569871 Free PMC article.
Combination therapy in treatment of experimental pulmonary aspergillosis: in vitro and in vivo correlations of the concentration- and dose- dependent interactions between anidulafungin and voriconazole by Bliss independence drug interaction analysis.
Petraitis V, Petraitiene R, Hope WW, Meletiadis J, Mickiene D, Hughes JE, Cotton MP, Stergiopoulou T, Kasai M, Francesconi A, Schaufele RL, Sein T, Avila NA, Bacher J, Walsh TJ. Petraitis V, et al. Among authors: sein t. Antimicrob Agents Chemother. 2009 Jun;53(6):2382-91. doi: 10.1128/AAC.00329-09. Epub 2009 Mar 23. Antimicrob Agents Chemother. 2009. PMID: 19307368 Free PMC article.
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