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Inhibition of NF-kappa B activation by peptides targeting NF-kappa B essential modulator (nemo) oligomerization.
Agou F, Courtois G, Chiaravalli J, Baleux F, Coïc YM, Traincard F, Israël A, Véron M. Agou F, et al. Among authors: courtois g. J Biol Chem. 2004 Dec 24;279(52):54248-57. doi: 10.1074/jbc.M406423200. Epub 2004 Oct 5. J Biol Chem. 2004. PMID: 15466857 Free article.
The minimal oligomerization domain of this protein consists of two coiled-coil subdomains named Coiled-coil 2 (CC2) and leucine zipper (LZ) (Agou, F., Traincard, F., Vinolo, E., Courtois, G., Yamaoka, S., Israel, A., and Veron, M. (2004) J. Biol. Chem. 279, 27861-27 …
The minimal oligomerization domain of this protein consists of two coiled-coil subdomains named Coiled-coil 2 (CC2) and leucine zipper (LZ) …
NEMO trimerizes through its coiled-coil C-terminal domain.
Agou F, Ye F, Goffinont S, Courtois G, Yamaoka S, Israël A, Véron M. Agou F, et al. Among authors: courtois g. J Biol Chem. 2002 May 17;277(20):17464-75. doi: 10.1074/jbc.M201964200. Epub 2002 Mar 4. J Biol Chem. 2002. PMID: 11877453 Free article.
A point mutation in NEMO associated with anhidrotic ectodermal dysplasia with immunodeficiency pathology results in destabilization of the oligomer and reduces lipopolysaccharide- and tumor necrosis factor-mediated NF-kappa B activation.
Vinolo E, Sebban H, Chaffotte A, Israël A, Courtois G, Véron M, Agou F. Vinolo E, et al. Among authors: courtois g. J Biol Chem. 2006 Mar 10;281(10):6334-48. doi: 10.1074/jbc.M510118200. Epub 2005 Dec 26. J Biol Chem. 2006. PMID: 16379012 Free article.
IKK regulation and human genetics.
Courtois G, Israël A. Courtois G, et al. Curr Top Microbiol Immunol. 2011;349:73-95. doi: 10.1007/82_2010_98. Curr Top Microbiol Immunol. 2011. PMID: 20845108 Review.
164 results