Bunnell SC - Search Results

1

PTEN permits acute increases in D3-phosphoinositide levels following TCR stimulation but inhibits distal signaling events by reducing the basal activity of Akt.

Seminario MC, Precht P, Bunnell SC, Warren SE, Morris CM, Taub D, Wange RL. Seminario MC, et al. Among authors: bunnell sc. Eur J Immunol. 2004 Nov;34(11):3165-75. doi: 10.1002/eji.200425206. Eur J Immunol. 2004. PMID: 15468057 Free article.

2

Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation.

Shan X, Czar MJ, Bunnell SC, Liu P, Liu Y, Schwartzberg PL, Wange RL. Shan X, et al. Among authors: bunnell sc. Mol Cell Biol. 2000 Sep;20(18):6945-57. doi: 10.1128/MCB.20.18.6945-6957.2000. Mol Cell Biol. 2000. PMID: 10958690 Free PMC article.

3

Dynamic molecular interactions linking the T cell antigen receptor to the actin cytoskeleton.

Barda-Saad M, Braiman A, Titerence R, Bunnell SC, Barr VA, Samelson LE. Barda-Saad M, et al. Among authors: bunnell sc. Nat Immunol. 2005 Jan;6(1):80-9. doi: 10.1038/ni1143. Epub 2004 Nov 21. Nat Immunol. 2005. PMID: 15558067

4

Persistence of cooperatively stabilized signaling clusters drives T-cell activation.

Bunnell SC, Singer AL, Hong DI, Jacque BH, Jordan MS, Seminario MC, Barr VA, Koretzky GA, Samelson LE. Bunnell SC, et al. Mol Cell Biol. 2006 Oct;26(19):7155-66. doi: 10.1128/MCB.00507-06. Mol Cell Biol. 2006. PMID: 16980618 Free PMC article.

5

Signal initiation in T-cell receptor microclusters.

Seminario MC, Bunnell SC. Seminario MC, et al. Among authors: bunnell sc. Immunol Rev. 2008 Feb;221:90-106. doi: 10.1111/j.1600-065X.2008.00593.x. Immunol Rev. 2008. PMID: 18275477 Review.

6

ADAP is an upstream regulator that precedes SLP-76 at sites of TCR engagement and stabilizes signaling microclusters.

Lewis JB, Scangarello FA, Murphy JM, Eidell KP, Sodipo MO, Ophir MJ, Sargeant R, Seminario MC, Bunnell SC. Lewis JB, et al. Among authors: bunnell sc. J Cell Sci. 2018 Nov 8;131(21):jcs215517. doi: 10.1242/jcs.215517. J Cell Sci. 2018. PMID: 30305305 Free PMC article.

7

Vav2 lacks Ca²⁺ entry-promoting scaffolding functions unique to Vav1 and inhibits T cell activation via Cdc42.

Fray MA, Charpentier JC, Sylvain NR, Seminario MC, Bunnell SC. Fray MA, et al. Among authors: bunnell sc. J Cell Sci. 2020 Mar 13;133(5):jcs238337. doi: 10.1242/jcs.238337. J Cell Sci. 2020. PMID: 31974114 Free PMC article.

8

LFA-1 and kindlin-3 enable the collaborative transport of SLP-76 microclusters by myosin and dynein motors.

Eidell KP, Lovy A, Sylvain NR, Scangarello FA, Muendlein HI, Ophir MJ, Nguyen K, Seminario MC, Bunnell SC. Eidell KP, et al. Among authors: bunnell sc. J Cell Sci. 2021 Aug 15;134(16):jcs258602. doi: 10.1242/jcs.258602. Epub 2021 Aug 27. J Cell Sci. 2021. PMID: 34279667 Free PMC article.

9

Lck phosphorylates the activation loop tyrosine of the Itk kinase domain and activates Itk kinase activity.

Heyeck SD, Wilcox HM, Bunnell SC, Berg LJ. Heyeck SD, et al. Among authors: bunnell sc. J Biol Chem. 1997 Oct 3;272(40):25401-8. doi: 10.1074/jbc.272.40.25401. J Biol Chem. 1997. PMID: 9312162 Free article.

10

Dynamic actin polymerization drives T cell receptor-induced spreading: a role for the signal transduction adaptor LAT.

Bunnell SC, Kapoor V, Trible RP, Zhang W, Samelson LE. Bunnell SC, et al. Immunity. 2001 Mar;14(3):315-29. doi: 10.1016/s1074-7613(01)00112-1. Immunity. 2001. PMID: 11290340 Free article.

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