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Targeted introduction of V642I mutation in amyloid precursor protein gene causes functional abnormality resembling early stage of Alzheimer's disease in aged mice.
Kawasumi M, Chiba T, Yamada M, Miyamae-Kaneko M, Matsuoka M, Nakahara J, Tomita T, Iwatsubo T, Kato S, Aiso S, Nishimoto I, Kouyama K. Kawasumi M, et al. Among authors: nishimoto i. Eur J Neurosci. 2004 May;19(10):2826-38. doi: 10.1111/j.0953-816X.2004.03397.x. Eur J Neurosci. 2004. PMID: 15147316
Humanin: after the discovery.
Niikura T, Chiba T, Aiso S, Matsuoka M, Nishimoto I. Niikura T, et al. Among authors: nishimoto i. Mol Neurobiol. 2004 Dec;30(3):327-40. doi: 10.1385/MN:30:3:327. Mol Neurobiol. 2004. PMID: 15655255 Review.
Insulin-like growth factor I (IGF-I) protects cells from apoptosis by Alzheimer's V642I mutant amyloid precursor protein through IGF-I receptor in an IGF-binding protein-sensitive manner.
Niikura T, Hashimoto Y, Okamoto T, Abe Y, Yasukawa T, Kawasumi M, Hiraki T, Kita Y, Terashita K, Kouyama K, Nishimoto I. Niikura T, et al. Among authors: nishimoto i. J Neurosci. 2001 Mar 15;21(6):1902-10. doi: 10.1523/JNEUROSCI.21-06-01902.2001. J Neurosci. 2001. PMID: 11245675 Free PMC article.
209 results