Koren AO - Search Results

1

Evaluation of 5-(2-(4-pyridinyl)vinyl)-6-chloro-3-(1-methyl-2-(S)-pyrrolidinylmethoxy)pyridine and its analogues as PET radioligands for imaging nicotinic acetylcholine receptors.

Brown L, Chefer S, Pavlova O, Vaupel DB, Koren AO, Kimes AS, Horti AG, Mukhin AG. Brown L, et al. Among authors: koren ao. J Neurochem. 2004 Nov;91(3):600-12. doi: 10.1111/j.1471-4159.2004.02762.x. J Neurochem. 2004. PMID: 15485491 Free article.

2

Synthesis and evaluation of a novel series of 2-chloro-5-((1-methyl-2-(S)-pyrrolidinyl)methoxy)-3-(2-(4-pyridinyl)vinyl)pyridine analogues as potential positron emission tomography imaging agents for nicotinic acetylcholine receptors.

Brown LL, Kulkarni S, Pavlova OA, Koren AO, Mukhin AG, Newman AH, Horti AG. Brown LL, et al. Among authors: koren ao. J Med Chem. 2002 Jun 20;45(13):2841-9. doi: 10.1021/jm010550n. J Med Chem. 2002. PMID: 12061886

3

Graphical analysis of 2-[18F]FA binding to nicotinic acetylcholine receptors in rhesus monkey brain.

Chefer SI, London ED, Koren AO, Pavlova OA, Kurian V, Kimes AS, Horti AG, Mukhin AG. Chefer SI, et al. Among authors: koren ao. Synapse. 2003 Apr;48(1):25-34. doi: 10.1002/syn.10180. Synapse. 2003. PMID: 12557269

4

2-[18F]F-A-85380: PET imaging of brain nicotinic acetylcholine receptors and whole body distribution in humans.

Kimes AS, Horti AG, London ED, Chefer SI, Contoreggi C, Ernst M, Friello P, Koren AO, Kurian V, Matochik JA, Pavlova O, Vaupel DB, Mukhin AG. Kimes AS, et al. Among authors: koren ao. FASEB J. 2003 Jul;17(10):1331-3. doi: 10.1096/fj.02-0492fje. Epub 2003 May 20. FASEB J. 2003. PMID: 12759330

5

Pharmacological and toxicological evaluation of 2-fluoro-3-(2(S)-azetidinylmethoxy)pyridine (2-F-A-85380), a ligand for imaging cerebral nicotinic acetylcholine receptors with positron emission tomography.

Vaupel DB, Tella SR, Huso DL, Wagner VO 3rd, Mukhin AG, Chefer SI, Horti AG, London ED, Koren AO, Kimes AS. Vaupel DB, et al. Among authors: koren ao. J Pharmacol Exp Ther. 2005 Jan;312(1):355-65. doi: 10.1124/jpet.104.073999. Epub 2004 Aug 26. J Pharmacol Exp Ther. 2005. PMID: 15331657

6

In vitro characterization of 6-[18F]fluoro-A-85380, a high-affinity ligand for alpha4beta2* nicotinic acetylcholine receptors.

Gündisch D, Koren AO, Horti AG, Pavlova OA, Kimes AS, Mukhin AG, London ED. Gündisch D, et al. Among authors: koren ao. Synapse. 2005 Feb;55(2):89-97. doi: 10.1002/syn.20096. Synapse. 2005. PMID: 15529332

7

In vivo studies with [125I]5-I-A-85380, a nicotinic acetylcholine receptor radioligand.

Vaupel DB, Mukhin AG, Kimes AS, Horti AG, Koren AO, London ED. Vaupel DB, et al. Among authors: koren ao. Neuroreport. 1998 Jul 13;9(10):2311-7. doi: 10.1097/00001756-199807130-00030. Neuroreport. 1998. PMID: 9694220

8

2-, 5-, and 6-Halo-3-(2(S)-azetidinylmethoxy)pyridines: synthesis, affinity for nicotinic acetylcholine receptors, and molecular modeling.

Koren AO, Horti AG, Mukhin AG, Gündisch D, Kimes AS, Dannals RF, London ED. Koren AO, et al. J Med Chem. 1998 Sep 10;41(19):3690-8. doi: 10.1021/jm980170a. J Med Chem. 1998. PMID: 9733494

9

In vivo imaging of brain nicotinic acetylcholine receptors with 5-[123I]iodo-A-85380 using single photon emission computed tomography.

Chefer SI, Horti AG, Lee KS, Koren AO, Jones DW, Gorey JG, Links JM, Mukhin AG, Weinberger DR, London ED. Chefer SI, et al. Among authors: koren ao. Life Sci. 1998;63(25):PL355-60. doi: 10.1016/s0024-3205(98)00514-1. Life Sci. 1998. PMID: 9870715

10

Radiosynthesis and preliminary evaluation of 5-[123/125I]iodo-3-(2(S)-azetidinylmethoxy)pyridine: a radioligand for nicotinic acetylcholine receptors.

Horti AG, Koren AO, Lee KS, Mukhin AG, Vaupel DB, Kimes AS, Stratton M, London ED. Horti AG, et al. Among authors: koren ao. Nucl Med Biol. 1999 Feb;26(2):175-82. doi: 10.1016/s0969-8051(98)00086-9. Nucl Med Biol. 1999. PMID: 10100216

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