Greenlee WJ - Search Results

1

Synthesis and use of 3-amino-4-phenyl-2-piperidones and 4-amino-2-benzazepin-3-ones as conformationally restricted phenylalanine isosteres in renin inhibitors.

de Laszlo SE, Bush BL, Doyle JJ, Greenlee WJ, Hangauer DG, Halgren TA, Lynch RJ, Schorn TW, Siegl PK. de Laszlo SE, et al. Among authors: greenlee wj. J Med Chem. 1992 Mar 6;35(5):833-46. doi: 10.1021/jm00083a006. J Med Chem. 1992. PMID: 1548675

2

Inhibitors of human renin with C-termini derived from amides and esters of alpha-mercaptoalkanoic acids.

Ashton WT, Cantone CL, Tolman RL, Greenlee WJ, Lynch RJ, Schorn TW, Strouse JF, Siegl PK. Ashton WT, et al. Among authors: greenlee wj. J Med Chem. 1992 Jul 24;35(15):2772-81. doi: 10.1021/jm00093a009. J Med Chem. 1992. PMID: 1495010

3

Renin inhibitors containing C-termini derived from mercaptoheterocycles.

Ashton WT, Cantone CL, Meurer LC, Tolman RL, Greenlee WJ, Patchett AA, Lynch RJ, Schorn TW, Strouse JF, Siegl PK. Ashton WT, et al. Among authors: greenlee wj. J Med Chem. 1992 May 29;35(11):2103-12. doi: 10.1021/jm00089a023. J Med Chem. 1992. PMID: 1597860

4

In vitro pharmacology of L-158,809, a new highly potent and selective angiotensin II receptor antagonist.

Chang RS, Siegl PK, Clineschmidt BV, Mantlo NB, Chakravarty PK, Greenlee WJ, Patchett AA, Lotti VJ. Chang RS, et al. Among authors: greenlee wj. J Pharmacol Exp Ther. 1992 Jul;262(1):133-8. J Pharmacol Exp Ther. 1992. PMID: 1625192

5

In vivo pharmacology of L-158,809, a new highly potent and selective nonpeptide angiotensin II receptor antagonist.

Siegl PK, Chang RS, Mantlo NB, Chakravarty PK, Ondeyka DL, Greenlee WJ, Patchett AA, Sweet CS, Lotti VJ. Siegl PK, et al. Among authors: greenlee wj. J Pharmacol Exp Ther. 1992 Jul;262(1):139-44. J Pharmacol Exp Ther. 1992. PMID: 1625193

6

Design and synthesis of P2-P1'-linked macrocyclic human renin inhibitors.

Weber AE, Halgren TA, Doyle JJ, Lynch RJ, Siegl PK, Parsons WH, Greenlee WJ, Patchett AA. Weber AE, et al. Among authors: greenlee wj. J Med Chem. 1991 Sep;34(9):2692-701. doi: 10.1021/jm00113a005. J Med Chem. 1991. PMID: 1895289

7

Acute hypotensive responses to peptide inhibitors of renin in conscious monkeys: an effect on blood pressure independent of plasma renin inhibition.

Schaffer LW, Schorn TW, Winquist RJ, Strouse JF, Payne L, Chakravarty PK, de Laszlo SE, tenBroeke J, Veber DF, Greenlee WJ, et al. Schaffer LW, et al. Among authors: greenlee wj. J Hypertens. 1990 Mar;8(3):251-9. J Hypertens. 1990. PMID: 2159506

8

Renin inhibitors.

Greenlee WJ. Greenlee WJ. Med Res Rev. 1990 Apr-Jun;10(2):173-236. doi: 10.1002/med.2610100203. Med Res Rev. 1990. PMID: 2184298 Review.

9

(3-Amino-2-oxoalkyl)phosphonic acids and their analogues as novel inhibitors of D-alanine:D-alanine ligase.

Chakravarty PK, Greenlee WJ, Parsons WH, Patchett AA, Combs P, Roth A, Busch RD, Mellin TN. Chakravarty PK, et al. Among authors: greenlee wj. J Med Chem. 1989 Aug;32(8):1886-90. doi: 10.1021/jm00128a033. J Med Chem. 1989. PMID: 2502630

10

Design of a selective insulin receptor tyrosine kinase inhibitor and its effect on glucose uptake and metabolism in intact cells.

Saperstein R, Vicario PP, Strout HV, Brady E, Slater EE, Greenlee WJ, Ondeyka DL, Patchett AA, Hangauer DG. Saperstein R, et al. Among authors: greenlee wj. Biochemistry. 1989 Jun 27;28(13):5694-701. doi: 10.1021/bi00439a053. Biochemistry. 1989. PMID: 2550060

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