Govaerts C - Search Results

1

Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humans.

Srinivasan S, Lubrano-Berthelier C, Govaerts C, Picard F, Santiago P, Conklin BR, Vaisse C. Srinivasan S, et al. Among authors: govaerts c. J Clin Invest. 2004 Oct;114(8):1158-64. doi: 10.1172/JCI21927. J Clin Invest. 2004. PMID: 15489963 Free PMC article.

2

Mechanism of N-terminal modulation of activity at the melanocortin-4 receptor GPCR.

Ersoy BA, Pardo L, Zhang S, Thompson DA, Millhauser G, Govaerts C, Vaisse C. Ersoy BA, et al. Among authors: govaerts c. Nat Chem Biol. 2012 Aug;8(8):725-30. doi: 10.1038/nchembio.1008. Epub 2012 Jun 24. Nat Chem Biol. 2012. PMID: 22729149 Free PMC article.

3

Obesity-associated mutations in the melanocortin 4 receptor provide novel insights into its function.

Govaerts C, Srinivasan S, Shapiro A, Zhang S, Picard F, Clement K, Lubrano-Berthelier C, Vaisse C. Govaerts C, et al. Peptides. 2005 Oct;26(10):1909-19. doi: 10.1016/j.peptides.2004.11.042. Peptides. 2005. PMID: 16083993 Review.

4

Molecular genetics of human obesity-associated MC4R mutations.

Lubrano-Berthelier C, Cavazos M, Dubern B, Shapiro A, Stunff CL, Zhang S, Picart F, Govaerts C, Froguel P, Bougneres P, Clement K, Vaisse C. Lubrano-Berthelier C, et al. Among authors: govaerts c. Ann N Y Acad Sci. 2003 Jun;994:49-57. doi: 10.1111/j.1749-6632.2003.tb03161.x. Ann N Y Acad Sci. 2003. PMID: 12851297 Review.

5

A 50-A separation of the integrin alpha v beta 3 extracellular domain C termini reveals an intermediate activation state.

Gline SE, Cambier S, Govaerts C, Nishimura SL. Gline SE, et al. Among authors: govaerts c. J Biol Chem. 2004 Dec 24;279(52):54567-72. doi: 10.1074/jbc.M406582200. Epub 2004 Oct 8. J Biol Chem. 2004. PMID: 15475365 Free article.

6

Evidence for assembly of prions with left-handed beta-helices into trimers.

Govaerts C, Wille H, Prusiner SB, Cohen FE. Govaerts C, et al. Proc Natl Acad Sci U S A. 2004 Jun 1;101(22):8342-7. doi: 10.1073/pnas.0402254101. Epub 2004 May 21. Proc Natl Acad Sci U S A. 2004. PMID: 15155909 Free PMC article.

7

NH2 terminus of serum and glucocorticoid-regulated kinase 1 binds to phosphoinositides and is essential for isoform-specific physiological functions.

Pao AC, McCormick JA, Li H, Siu J, Govaerts C, Bhalla V, Soundararajan R, Pearce D. Pao AC, et al. Among authors: govaerts c. Am J Physiol Renal Physiol. 2007 Jun;292(6):F1741-50. doi: 10.1152/ajprenal.00027.2007. Epub 2007 Mar 13. Am J Physiol Renal Physiol. 2007. PMID: 17356130 Free article.

8

Site-directed mutagenesis demonstrates the plasticity of the beta helix: implications for the structure of the misfolded prion protein.

Choi JH, May BC, Govaerts C, Cohen FE. Choi JH, et al. Among authors: govaerts c. Structure. 2009 Jul 15;17(7):1014-23. doi: 10.1016/j.str.2009.05.013. Structure. 2009. PMID: 19604481 Free article.

9

Developing therapeutics for the diseases of protein misfolding.

May BC, Govaerts C, Cohen FE. May BC, et al. Among authors: govaerts c. Neurology. 2006 Jan 24;66(2 Suppl 1):S118-22. doi: 10.1212/01.wnl.0000192309.26571.a7. Neurology. 2006. PMID: 16432139 Review.

10

Analysis of the sequence and structural features of the left-handed beta-helical fold.

Choi JH, Govaerts C, May BC, Cohen FE. Choi JH, et al. Among authors: govaerts c. Proteins. 2008 Oct;73(1):150-60. doi: 10.1002/prot.22051. Proteins. 2008. PMID: 18398908

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