Incles CM - Search Results

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Evaluation of by disubstituted acridone derivatives as telomerase inhibitors: the importance of G-quadruplex binding.

Harrison RJ, Reszka AP, Haider SM, Romagnoli B, Morrell J, Read MA, Gowan SM, Incles CM, Kelland LR, Neidle S. Harrison RJ, et al. Among authors: incles cm. Bioorg Med Chem Lett. 2004 Dec 6;14(23):5845-9. doi: 10.1016/j.bmcl.2004.09.037. Bioorg Med Chem Lett. 2004. PMID: 15501053

Telomerase inhibitors in cancer therapy: current status and future directions.

Incles CM, Schultes CM, Neidle S. Incles CM, et al. Curr Opin Investig Drugs. 2003 Jun;4(6):675-85. Curr Opin Investig Drugs. 2003. PMID: 12901225 Review.

Trisubstituted acridine derivatives as potent and selective telomerase inhibitors.

Harrison RJ, Cuesta J, Chessari G, Read MA, Basra SK, Reszka AP, Morrell J, Gowan SM, Incles CM, Tanious FA, Wilson WD, Kelland LR, Neidle S. Harrison RJ, et al. Among authors: incles cm. J Med Chem. 2003 Oct 9;46(21):4463-76. doi: 10.1021/jm0308693. J Med Chem. 2003. PMID: 14521409

Acquired cellular resistance to flavopiridol in a human colon carcinoma cell line involves up-regulation of the telomerase catalytic subunit and telomere elongation. Sensitivity of resistant cells to combination treatment with a telomerase inhibitor.

Incles CM, Schultes CM, Kelland LR, Neidle S. Incles CM, et al. Mol Pharmacol. 2003 Nov;64(5):1101-8. doi: 10.1124/mol.64.5.1101. Mol Pharmacol. 2003. PMID: 14573759

A G-quadruplex telomere targeting agent produces p16-associated senescence and chromosomal fusions in human prostate cancer cells.

Incles CM, Schultes CM, Kempski H, Koehler H, Kelland LR, Neidle S. Incles CM, et al. Mol Cancer Ther. 2004 Oct;3(10):1201-6. Mol Cancer Ther. 2004. PMID: 15486186

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