Schwäble J - Search Results

1

RGS2 is an important target gene of Flt3-ITD mutations in AML and functions in myeloid differentiation and leukemic transformation.

Schwäble J, Choudhary C, Thiede C, Tickenbrock L, Sargin B, Steur C, Rehage M, Rudat A, Brandts C, Berdel WE, Müller-Tidow C, Serve H. Schwäble J, et al. Blood. 2005 Mar 1;105(5):2107-14. doi: 10.1182/blood-2004-03-0940. Epub 2004 Nov 9. Blood. 2005. PMID: 15536149 Free article.

2

Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations.

Mizuki M, Schwable J, Steur C, Choudhary C, Agrawal S, Sargin B, Steffen B, Matsumura I, Kanakura Y, Böhmer FD, Müller-Tidow C, Berdel WE, Serve H. Mizuki M, et al. Among authors: schwable j. Blood. 2003 Apr 15;101(8):3164-73. doi: 10.1182/blood-2002-06-1677. Epub 2002 Dec 5. Blood. 2003. PMID: 12468433 Free article.

3

Flt3 tandem duplication mutations cooperate with Wnt signaling in leukemic signal transduction.

Tickenbrock L, Schwäble J, Wiedehage M, Steffen B, Sargin B, Choudhary C, Brandts C, Berdel WE, Müller-Tidow C, Serve H. Tickenbrock L, et al. Among authors: schwable j. Blood. 2005 May 1;105(9):3699-706. doi: 10.1182/blood-2004-07-2924. Epub 2005 Jan 13. Blood. 2005. PMID: 15650056 Free article.

4

AML-associated Flt3 kinase domain mutations show signal transduction differences compared with Flt3 ITD mutations.

Choudhary C, Schwäble J, Brandts C, Tickenbrock L, Sargin B, Kindler T, Fischer T, Berdel WE, Müller-Tidow C, Serve H. Choudhary C, et al. Among authors: schwable j. Blood. 2005 Jul 1;106(1):265-73. doi: 10.1182/blood-2004-07-2942. Epub 2005 Mar 15. Blood. 2005. PMID: 15769897 Free article.

5

The molecular pathogenesis of acute myeloid leukemia.

Steffen B, Müller-Tidow C, Schwäble J, Berdel WE, Serve H. Steffen B, et al. Among authors: schwable j. Crit Rev Oncol Hematol. 2005 Nov;56(2):195-221. doi: 10.1016/j.critrevonc.2004.10.012. Epub 2005 Oct 19. Crit Rev Oncol Hematol. 2005. PMID: 16236521 Review.

6

Constitutive activation of Akt by Flt3 internal tandem duplications is necessary for increased survival, proliferation, and myeloid transformation.

Brandts CH, Sargin B, Rode M, Biermann C, Lindtner B, Schwäble J, Buerger H, Müller-Tidow C, Choudhary C, McMahon M, Berdel WE, Serve H. Brandts CH, et al. Among authors: schwable j. Cancer Res. 2005 Nov 1;65(21):9643-50. doi: 10.1158/0008-5472.CAN-05-0422. Cancer Res. 2005. PMID: 16266983

7

Activation mechanisms of STAT5 by oncogenic Flt3-ITD.

Choudhary C, Brandts C, Schwable J, Tickenbrock L, Sargin B, Ueker A, Böhmer FD, Berdel WE, Müller-Tidow C, Serve H. Choudhary C, et al. Among authors: schwable j. Blood. 2007 Jul 1;110(1):370-4. doi: 10.1182/blood-2006-05-024018. Epub 2007 Mar 13. Blood. 2007. PMID: 17356133 Free article.

8

Flt3-dependent transformation by inactivating c-Cbl mutations in AML.

Sargin B, Choudhary C, Crosetto N, Schmidt MHH, Grundler R, Rensinghoff M, Thiessen C, Tickenbrock L, Schwäble J, Brandts C, August B, Koschmieder S, Bandi SR, Duyster J, Berdel WE, Müller-Tidow C, Dikic I, Serve H. Sargin B, et al. Among authors: schwable j. Blood. 2007 Aug 1;110(3):1004-12. doi: 10.1182/blood-2007-01-066076. Epub 2007 Apr 19. Blood. 2007. PMID: 17446348 Free article. Clinical Trial.

9

[Mutations of growth factor receptor Flt3 in acute myeloid leukemia: transformation of myeloid cells by Ras-dependent and Ras-independent mechanisms].

Müller-Tidow C, Steur C, Mizuki M, Schwäble J, Brandts C, Berdel WE, Serve H. Müller-Tidow C, et al. Among authors: schwable j. Dtsch Med Wochenschr. 2002 Oct 18;127(42):2195-200. doi: 10.1055/s-2002-34942. Dtsch Med Wochenschr. 2002. PMID: 12397548 German.

10

High-throughput analysis of genome-wide receptor tyrosine kinase expression in human cancers identifies potential novel drug targets.

Müller-Tidow C, Schwäble J, Steffen B, Tidow N, Brandt B, Becker K, Schulze-Bahr E, Halfter H, Vogt U, Metzger R, Schneider PM, Büchner T, Brandts C, Berdel WE, Serve H. Müller-Tidow C, et al. Among authors: schwable j. Clin Cancer Res. 2004 Feb 15;10(4):1241-9. doi: 10.1158/1078-0432.ccr-0954-03. Clin Cancer Res. 2004. PMID: 14977821

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