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Prolonged survival of mice with multiple liver metastases of human colon cancer by intravenous administration of replicable E1B-55K-deleted adenovirus with E1A expressed by CEA promoter.
Sagawa T, Takahashi M, Sato T, Sato Y, Lu Y, Sumiyoshi T, Yamada Y, Iyama S, Fukaura J, Sasaki K, Hamada H, Miyanishi K, Takayama T, Kato J, Niitsu Y. Sagawa T, et al. Among authors: yamada y. Mol Ther. 2004 Dec;10(6):1043-50. doi: 10.1016/j.ymthe.2004.08.023. Mol Ther. 2004. PMID: 15564136 Free article.
E1B-55K-deleted adenovirus expressing E1A-13S by AFP-enhancer/promoter is capable of highly specific replication in AFP-producing hepatocellular carcinoma and eradication of established tumor.
Takahashi M, Sato T, Sagawa T, Lu Y, Sato Y, Iyama S, Yamada Y, Fukaura J, Takahashi S, Miyanishi K, Yamashita T, Sasaki K, Kogawa K, Hamada H, Kato J, Niitsu Y. Takahashi M, et al. Among authors: yamada y. Mol Ther. 2002 May;5(5 Pt 1):627-34. doi: 10.1006/mthe.2002.0589. Mol Ther. 2002. PMID: 11991754 Free article.
9,929 results