Burel SA - Search Results

1

Deletion of an AML1-ETO C-terminal NcoR/SMRT-interacting region strongly induces leukemia development.

Yan M, Burel SA, Peterson LF, Kanbe E, Iwasaki H, Boyapati A, Hines R, Akashi K, Zhang DE. Yan M, et al. Among authors: burel sa. Proc Natl Acad Sci U S A. 2004 Dec 7;101(49):17186-91. doi: 10.1073/pnas.0406702101. Epub 2004 Nov 29. Proc Natl Acad Sci U S A. 2004. PMID: 15569932 Free PMC article.

2

Dichotomy of AML1-ETO functions: growth arrest versus block of differentiation.

Burel SA, Harakawa N, Zhou L, Pabst T, Tenen DG, Zhang DE. Burel SA, et al. Mol Cell Biol. 2001 Aug;21(16):5577-90. doi: 10.1128/MCB.21.16.5577-5590.2001. Mol Cell Biol. 2001. PMID: 11463839 Free PMC article.

3

AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations.

Yuan Y, Zhou L, Miyamoto T, Iwasaki H, Harakawa N, Hetherington CJ, Burel SA, Lagasse E, Weissman IL, Akashi K, Zhang DE. Yuan Y, et al. Among authors: burel sa. Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10398-403. doi: 10.1073/pnas.171321298. Proc Natl Acad Sci U S A. 2001. PMID: 11526243 Free PMC article.

4

AML1 and AML1 fusion protein AML1-ETO in myeloid gene regulation and leukemogenesis.

Zhang DE, Burel S, Zhou L, Hetherington CJ, Yuan Y. Zhang DE, et al. Blood Cells Mol Dis. 2001 Mar-Apr;27(2):368-76. doi: 10.1006/bcmd.2001.0391. Blood Cells Mol Dis. 2001. PMID: 11259158 No abstract available.

5

Non-CpG-containing antisense 2'-methoxyethyl oligonucleotides activate a proinflammatory response independent of Toll-like receptor 9 or myeloid differentiation factor 88.

Senn JJ, Burel S, Henry SP. Senn JJ, et al. J Pharmacol Exp Ther. 2005 Sep;314(3):972-9. doi: 10.1124/jpet.105.084004. Epub 2005 May 26. J Pharmacol Exp Ther. 2005. PMID: 15919763 Free article.

6

Unique O-methoxyethyl ribose-DNA chimeric oligonucleotide induces an atypical melanoma differentiation-associated gene 5-dependent induction of type I interferon response.

Burel SA, Machemer T, Ragone FL, Kato H, Cauntay P, Greenlee S, Salim A, Gaarde WA, Hung G, Peralta R, Freier SM, Henry SP. Burel SA, et al. J Pharmacol Exp Ther. 2012 Jul;342(1):150-62. doi: 10.1124/jpet.112.193789. Epub 2012 Apr 13. J Pharmacol Exp Ther. 2012. PMID: 22505629

7

Preclinical evaluation of the toxicological effects of a novel constrained ethyl modified antisense compound targeting signal transducer and activator of transcription 3 in mice and cynomolgus monkeys.

Burel SA, Han SR, Lee HS, Norris DA, Lee BS, Machemer T, Park SY, Zhou T, He G, Kim Y, MacLeod AR, Monia BP, Lio S, Kim TW, Henry SP. Burel SA, et al. Nucleic Acid Ther. 2013 Jun;23(3):213-27. doi: 10.1089/nat.2013.0422. Nucleic Acid Ther. 2013. PMID: 23692080

8

Assessment of the Effects of 2'-Methoxyethyl Antisense Oligonucleotides on Platelet Count in Cynomolgus Nonhuman Primates.

Henry SP, Narayanan P, Shen L, Bhanot S, Younis HS, Burel SA. Henry SP, et al. Among authors: burel sa. Nucleic Acid Ther. 2017 Aug;27(4):197-208. doi: 10.1089/nat.2017.0666. Epub 2017 May 25. Nucleic Acid Ther. 2017. PMID: 28541820

9

The Distinct and Cooperative Roles of Toll-Like Receptor 9 and Receptor for Advanced Glycation End Products in Modulating In Vivo Inflammatory Responses to Select CpG and Non-CpG Oligonucleotides.

Paz S, Hsiao J, Cauntay P, Soriano A, Bai L, Machemer T, Xiao X, Guo S, Hung G, Younis H, Bennett CF, Henry S, Yun TJ, Burel S. Paz S, et al. Nucleic Acid Ther. 2017 Oct;27(5):272-284. doi: 10.1089/nat.2017.0668. Epub 2017 Jun 12. Nucleic Acid Ther. 2017. PMID: 28605247

10

Safety, Pharmacokinetic, and Pharmacodynamic Evaluation of a 2'-(2-Methoxyethyl)-D-ribose Antisense Oligonucleotide-Triantenarry N-Acetyl-galactosamine Conjugate that Targets the Human Transmembrane Protease Serine 6.

Zanardi TA, Korbmacher B, Boone L, Engelhardt JA, Wang Y, Burel S, Prill B, Aghajan M, Guo S, Henry SP. Zanardi TA, et al. J Pharmacol Exp Ther. 2021 Apr;377(1):51-63. doi: 10.1124/jpet.120.000222. Epub 2021 Jan 11. J Pharmacol Exp Ther. 2021. PMID: 33431610

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