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Page 1
p38alpha mitogen-activated protein kinase plays a critical role in cardiomyocyte survival but not in cardiac hypertrophic growth in response to pressure overload.
Nishida K, Yamaguchi O, Hirotani S, Hikoso S, Higuchi Y, Watanabe T, Takeda T, Osuka S, Morita T, Kondoh G, Uno Y, Kashiwase K, Taniike M, Nakai A, Matsumura Y, Miyazaki J, Sudo T, Hongo K, Kusakari Y, Kurihara S, Chien KR, Takeda J, Hori M, Otsu K. Nishida K, et al. Among authors: hikoso s. Mol Cell Biol. 2004 Dec;24(24):10611-20. doi: 10.1128/MCB.24.24.10611-10620.2004. Mol Cell Biol. 2004. PMID: 15572667 Free PMC article.
Relationship Between Canagliflozin, Sodium Glucose Cotransporter 2 Inhibitor, and Hematopoietic Effects in Patients With Diabetes and Mild Heart Failure: Results From the CANDLE Trial.
Nakatani D, Dohi T, Hikoso S, Tanaka A, Nanasato M, Shimizu W, Node K, Sakata Y; CANDLE Trial Investigators. Nakatani D, et al. Among authors: hikoso s. J Cardiovasc Pharmacol. 2023 Jul 1;82(1):61-68. doi: 10.1097/FJC.0000000000001430. J Cardiovasc Pharmacol. 2023. PMID: 37070931 Clinical Trial.
Impact of Structural Abnormalities in Left Ventricle and Left Atrium on Clinical Outcomes in Heart Failure with Preserved Ejection Fraction.
Yano M, Nishino M, Kawanami S, Sugae H, Ukita K, Kawamura A, Yasumoto K, Tsuda M, Okamoto N, Matsunaga-Lee Y, Egami Y, Tanouchi J, Yamada T, Yasumura Y, Seo M, Hayashi T, Nakagawa A, Nakagawa Y, Tamaki S, Sotomi Y, Nakatani D, Hikoso S, Sakata Y; Osaka CardioVascular Conference (OCVC)-Heart Failure Investigators. Yano M, et al. Among authors: hikoso s. Int Heart J. 2023;64(5):875-884. doi: 10.1536/ihj.23-277. Int Heart J. 2023. PMID: 37778990 Free article.
Combination of Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios as a Novel Predictor of Cardiac Death in Patients With Acute Decompensated Heart Failure With Preserved Left Ventricular Ejection Fraction: A Multicenter Study.
Tamaki S, Nagai Y, Shutta R, Masuda D, Yamashita S, Seo M, Yamada T, Nakagawa A, Yasumura Y, Nakagawa Y, Yano M, Hayashi T, Hikoso S, Nakatani D, Sotomi Y, Sakata Y; OCVC‐Heart Failure Investigators. Tamaki S, et al. Among authors: hikoso s. J Am Heart Assoc. 2023 Jan 3;12(1):e026326. doi: 10.1161/JAHA.122.026326. Epub 2022 Dec 24. J Am Heart Assoc. 2023. PMID: 36565197 Free PMC article.
The small GTP-binding protein Rac1 induces cardiac myocyte hypertrophy through the activation of apoptosis signal-regulating kinase 1 and nuclear factor-kappa B.
Higuchi Y, Otsu K, Nishida K, Hirotani S, Nakayama H, Yamaguchi O, Hikoso S, Kashiwase K, Takeda T, Watanabe T, Mano T, Matsumura Y, Ueno H, Hori M. Higuchi Y, et al. Among authors: hikoso s. J Biol Chem. 2003 Jun 6;278(23):20770-7. doi: 10.1074/jbc.M213203200. Epub 2003 Apr 2. J Biol Chem. 2003. PMID: 12672819 Free article.
Targeted deletion of apoptosis signal-regulating kinase 1 attenuates left ventricular remodeling.
Yamaguchi O, Higuchi Y, Hirotani S, Kashiwase K, Nakayama H, Hikoso S, Takeda T, Watanabe T, Asahi M, Taniike M, Matsumura Y, Tsujimoto I, Hongo K, Kusakari Y, Kurihara S, Nishida K, Ichijo H, Hori M, Otsu K. Yamaguchi O, et al. Among authors: hikoso s. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15883-8. doi: 10.1073/pnas.2136717100. Epub 2003 Dec 9. Proc Natl Acad Sci U S A. 2003. PMID: 14665690 Free PMC article.
Ca(2+)-sensitive tyrosine kinase Pyk2/CAK beta-dependent signaling is essential for G-protein-coupled receptor agonist-induced hypertrophy.
Hirotani S, Higuchi Y, Nishida K, Nakayama H, Yamaguchi O, Hikoso S, Takeda T, Kashiwase K, Watanabe T, Asahi M, Taniike M, Tsujimoto I, Matsumura Y, Sasaki T, Hori M, Otsu K. Hirotani S, et al. Among authors: hikoso s. J Mol Cell Cardiol. 2004 Jun;36(6):799-807. doi: 10.1016/j.yjmcc.2004.03.002. J Mol Cell Cardiol. 2004. PMID: 15158121
Cardiac-specific overexpression of sarcolipin inhibits sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA2a) activity and impairs cardiac function in mice.
Asahi M, Otsu K, Nakayama H, Hikoso S, Takeda T, Gramolini AO, Trivieri MG, Oudit GY, Morita T, Kusakari Y, Hirano S, Hongo K, Hirotani S, Yamaguchi O, Peterson A, Backx PH, Kurihara S, Hori M, MacLennan DH. Asahi M, et al. Among authors: hikoso s. Proc Natl Acad Sci U S A. 2004 Jun 22;101(25):9199-204. doi: 10.1073/pnas.0402596101. Epub 2004 Jun 16. Proc Natl Acad Sci U S A. 2004. PMID: 15201433 Free PMC article.
174 results