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Concentrated RD114-pseudotyped MFGS-gp91phox vector achieves high levels of functional correction of the chronic granulomatous disease oxidase defect in NOD/SCID/beta -microglobulin-/- repopulating mobilized human peripheral blood CD34+ cells.
Brenner S, Whiting-Theobald NL, Linton GF, Holmes KL, Anderson-Cohen M, Kelly PF, Vanin EF, Pilon AM, Bodine DM, Horwitz ME, Malech HL. Brenner S, et al. Blood. 2003 Oct 15;102(8):2789-97. doi: 10.1182/blood-2002-05-1482. Epub 2003 Jun 26. Blood. 2003. PMID: 12829597 Free article.
WHIM syndrome myelokathexis reproduced in the NOD/SCID mouse xenotransplant model engrafted with healthy human stem cells transduced with C-terminus-truncated CXCR4.
Kawai T, Choi U, Cardwell L, DeRavin SS, Naumann N, Whiting-Theobald NL, Linton GF, Moon J, Murphy PM, Malech HL. Kawai T, et al. Among authors: whiting theobald nl. Blood. 2007 Jan 1;109(1):78-84. doi: 10.1182/blood-2006-05-025296. Epub 2006 Aug 31. Blood. 2007. PMID: 16946301 Free PMC article.
The late dividing population of gamma-retroviral vector transduced human mobilized peripheral blood progenitor cells contributes most to gene-marked cell engraftment in nonobese diabetic/severe combined immunodeficient mice.
Brenner S, Ryser MF, Whiting-Theobald NL, Gentsch M, Linton GF, Malech HL. Brenner S, et al. Among authors: whiting theobald nl. Stem Cells. 2007 Jul;25(7):1807-13. doi: 10.1634/stemcells.2006-0581. Epub 2007 Apr 26. Stem Cells. 2007. PMID: 17464090
Polyclonal long-term MFGS-gp91phox marking in rhesus macaques after nonmyeloablative transplantation with transduced autologous peripheral blood progenitor cells.
Brenner S, Ryser MF, Choi U, Whiting-Theobald N, Kuhlisch E, Linton G, Kang E, Lehmann R, Rosen-Wolff A, Rudikoff AG, Farese AM, Macvittie TJ, Roesler J, Horwitz ME, Malech HL. Brenner S, et al. Among authors: whiting theobald n. Mol Ther. 2006 Aug;14(2):202-11. doi: 10.1016/j.ymthe.2006.01.015. Epub 2006 Apr 5. Mol Ther. 2006. PMID: 16600688 Free article.
20 results