Gardner KH - Search Results

1

Identification of small-molecule antagonists that inhibit an activator: coactivator interaction.

Best JL, Amezcua CA, Mayr B, Flechner L, Murawsky CM, Emerson B, Zor T, Gardner KH, Montminy M. Best JL, et al. Among authors: gardner kh. Proc Natl Acad Sci U S A. 2004 Dec 21;101(51):17622-7. doi: 10.1073/pnas.0406374101. Epub 2004 Dec 7. Proc Natl Acad Sci U S A. 2004. PMID: 15585582 Free PMC article.

2

Structure and interactions of PAS kinase N-terminal PAS domain: model for intramolecular kinase regulation.

Amezcua CA, Harper SM, Rutter J, Gardner KH. Amezcua CA, et al. Among authors: gardner kh. Structure. 2002 Oct;10(10):1349-61. doi: 10.1016/s0969-2126(02)00857-2. Structure. 2002. PMID: 12377121 Free article.

3

Can you hear me now? Regulating transcriptional activators by phosphorylation.

Gardner KH, Montminy M. Gardner KH, et al. Sci STKE. 2005 Sep 13;2005(301):pe44. doi: 10.1126/stke.3012005pe44. Sci STKE. 2005. PMID: 16160121 Review.

4

Molecular basis of coiled coil coactivator recruitment by the aryl hydrocarbon receptor nuclear translocator (ARNT).

Partch CL, Card PB, Amezcua CA, Gardner KH. Partch CL, et al. Among authors: gardner kh. J Biol Chem. 2009 May 29;284(22):15184-92. doi: 10.1074/jbc.M808479200. Epub 2009 Mar 26. J Biol Chem. 2009. PMID: 19324882 Free PMC article.

5

Structural basis for PAS domain heterodimerization in the basic helix--loop--helix-PAS transcription factor hypoxia-inducible factor.

Erbel PJ, Card PB, Karakuzu O, Bruick RK, Gardner KH. Erbel PJ, et al. Among authors: gardner kh. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15504-9. doi: 10.1073/pnas.2533374100. Epub 2003 Dec 10. Proc Natl Acad Sci U S A. 2003. PMID: 14668441 Free PMC article.

6

ARNT PAS-B has a fragile native state structure with an alternative beta-sheet register nearby in sequence space.

Evans MR, Card PB, Gardner KH. Evans MR, et al. Among authors: gardner kh. Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2617-22. doi: 10.1073/pnas.0808270106. Epub 2009 Feb 5. Proc Natl Acad Sci U S A. 2009. PMID: 19196990 Free PMC article.

7

Mechanism of substrate specificity in Bacillus subtilis ResA, a thioredoxin-like protein involved in cytochrome c maturation.

Colbert CL, Wu Q, Erbel PJ, Gardner KH, Deisenhofer J. Colbert CL, et al. Among authors: gardner kh. Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4410-5. doi: 10.1073/pnas.0600552103. Epub 2006 Mar 13. Proc Natl Acad Sci U S A. 2006. PMID: 16537372 Free PMC article.

8

Coactivators necessary for transcriptional output of the hypoxia inducible factor, HIF, are directly recruited by ARNT PAS-B.

Partch CL, Gardner KH. Partch CL, et al. Among authors: gardner kh. Proc Natl Acad Sci U S A. 2011 May 10;108(19):7739-44. doi: 10.1073/pnas.1101357108. Epub 2011 Apr 21. Proc Natl Acad Sci U S A. 2011. PMID: 21512126 Free PMC article.

9

Structural basis of photosensitivity in a bacterial light-oxygen-voltage/helix-turn-helix (LOV-HTH) DNA-binding protein.

Nash AI, McNulty R, Shillito ME, Swartz TE, Bogomolni RA, Luecke H, Gardner KH. Nash AI, et al. Among authors: gardner kh. Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9449-54. doi: 10.1073/pnas.1100262108. Epub 2011 May 23. Proc Natl Acad Sci U S A. 2011. PMID: 21606338 Free PMC article.

10

Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor.

Scheuermann TH, Tomchick DR, Machius M, Guo Y, Bruick RK, Gardner KH. Scheuermann TH, et al. Among authors: gardner kh. Proc Natl Acad Sci U S A. 2009 Jan 13;106(2):450-5. doi: 10.1073/pnas.0808092106. Epub 2009 Jan 7. Proc Natl Acad Sci U S A. 2009. PMID: 19129502 Free PMC article.

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