Hasty P - Search Results

1

The impact of DNA damage, genetic mutation and cellular responses on cancer prevention, longevity and aging: observations in humans and mice.

Hasty P. Hasty P. Mech Ageing Dev. 2005 Jan;126(1):71-7. doi: 10.1016/j.mad.2004.09.036. Mech Ageing Dev. 2005. PMID: 15610764 Review.

2

RAD51 separation of function mutation disables replication fork maintenance but preserves DSB repair.

Son MY, Belan O, Spirek M, Cibulka J, Nikulenkov F, Kim YY, Hwang S, Myung K, Montagna C, Kim TM, Krejci L, Hasty P. Son MY, et al. Among authors: hasty p. iScience. 2024 Mar 16;27(4):109524. doi: 10.1016/j.isci.2024.109524. eCollection 2024 Apr 19. iScience. 2024. PMID: 38577109 Free PMC article.

3

The impact energy metabolism and genome maintenance have on longevity and senescence: lessons from yeast to mammals.

Hasty P. Hasty P. Mech Ageing Dev. 2001 Oct;122(15):1651-62. doi: 10.1016/s0047-6374(01)00294-9. Mech Ageing Dev. 2001. PMID: 11557271 Review.

4

Aging and genome maintenance: lessons from the mouse?

Hasty P, Campisi J, Hoeijmakers J, van Steeg H, Vijg J. Hasty P, et al. Science. 2003 Feb 28;299(5611):1355-9. doi: 10.1126/science.1079161. Science. 2003. PMID: 12610296 Review.

5

Accelerating aging by mouse reverse genetics: a rational approach to understanding longevity.

Hasty P, Vijg J. Hasty P, et al. Aging Cell. 2004 Apr;3(2):55-65. doi: 10.1111/j.1474-9728.2004.00082.x. Aging Cell. 2004. PMID: 15038819 Free article. Review.

6

A genotoxic screen: rapid analysis of cellular dose-response to a wide range of agents that either damage DNA or alter genome maintenance pathways.

Marple T, Li H, Hasty P. Marple T, et al. Among authors: hasty p. Mutat Res. 2004 Oct 4;554(1-2):253-66. doi: 10.1016/j.mrfmmm.2004.05.004. Mutat Res. 2004. PMID: 15450423

7

Extended longevity mechanisms in short-lived progeroid mice: identification of a preservative stress response associated with successful aging.

van de Ven M, Andressoo JO, Holcomb VB, Hasty P, Suh Y, van Steeg H, Garinis GA, Hoeijmakers JH, Mitchell JR. van de Ven M, et al. Among authors: hasty p. Mech Ageing Dev. 2007 Jan;128(1):58-63. doi: 10.1016/j.mad.2006.11.011. Epub 2006 Nov 28. Mech Ageing Dev. 2007. PMID: 17126380 Free PMC article. Review.

8

Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer.

Li H, Vogel H, Holcomb VB, Gu Y, Hasty P. Li H, et al. Among authors: hasty p. Mol Cell Biol. 2007 Dec;27(23):8205-14. doi: 10.1128/MCB.00785-07. Epub 2007 Sep 17. Mol Cell Biol. 2007. PMID: 17875923 Free PMC article.

9

Deletion of Ku80 causes early aging independent of chronic inflammation and Rag-1-induced DSBs.

Holcomb VB, Vogel H, Hasty P. Holcomb VB, et al. Among authors: hasty p. Mech Ageing Dev. 2007 Nov-Dec;128(11-12):601-8. doi: 10.1016/j.mad.2007.08.006. Epub 2007 Sep 12. Mech Ageing Dev. 2007. PMID: 17928034 Free PMC article.

10

DNA double-strand breaks: a potential causative factor for mammalian aging?

Li H, Mitchell JR, Hasty P. Li H, et al. Among authors: hasty p. Mech Ageing Dev. 2008 Jul-Aug;129(7-8):416-24. doi: 10.1016/j.mad.2008.02.002. Epub 2008 Feb 14. Mech Ageing Dev. 2008. PMID: 18346777 Free PMC article. Review.

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