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Page 1
Defining and assaying RNAi in mammalian cells.
Huppi K, Martin SE, Caplen NJ. Huppi K, et al. Among authors: caplen nj. Mol Cell. 2005 Jan 7;17(1):1-10. doi: 10.1016/j.molcel.2004.12.017. Mol Cell. 2005. PMID: 15629712 Free article. Review.
ETS1, a target gene of the EWSR1::FLI1 fusion oncoprotein, regulates the expression of the focal adhesion protein TENSIN3.
Ebegboni VJ, Jones TL, Brownmiller T, Zhao PX, Pehrsson EC, Rajan SS, Caplen NJ. Ebegboni VJ, et al. Among authors: caplen nj. bioRxiv [Preprint]. 2023 Dec 23:2023.12.21.572864. doi: 10.1101/2023.12.21.572864. bioRxiv. 2023. Update in: Mol Cancer Res. 2024 Jul 2;22(7):625-641. doi: 10.1158/1541-7786.MCR-23-1090 PMID: 38187702 Free PMC article. Updated. Preprint.
RNAi as a gene therapy approach.
Caplen NJ. Caplen NJ. Expert Opin Biol Ther. 2003 Jul;3(4):575-86. doi: 10.1517/14712598.3.4.575. Expert Opin Biol Ther. 2003. PMID: 12831363 Review.
Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells.
Scacheri PC, Rozenblatt-Rosen O, Caplen NJ, Wolfsberg TG, Umayam L, Lee JC, Hughes CM, Shanmugam KS, Bhattacharjee A, Meyerson M, Collins FS. Scacheri PC, et al. Among authors: caplen nj. Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):1892-7. doi: 10.1073/pnas.0308698100. Epub 2004 Feb 9. Proc Natl Acad Sci U S A. 2004. PMID: 14769924 Free PMC article.
Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells.
Lorenzi PL, Reinhold WC, Rudelius M, Gunsior M, Shankavaram U, Bussey KJ, Scherf U, Eichler GS, Martin SE, Chin K, Gray JW, Kohn EC, Horak ID, Von Hoff DD, Raffeld M, Goldsmith PK, Caplen NJ, Weinstein JN. Lorenzi PL, et al. Among authors: caplen nj. Mol Cancer Ther. 2006 Nov;5(11):2613-23. doi: 10.1158/1535-7163.MCT-06-0447. Epub 2006 Nov 6. Mol Cancer Ther. 2006. PMID: 17088436
86 results