Wu J - Search Results

1

Role for the epidermal growth factor receptor in neurofibromatosis-related peripheral nerve tumorigenesis.

Ling BC, Wu J, Miller SJ, Monk KR, Shamekh R, Rizvi TA, Decourten-Myers G, Vogel KS, DeClue JE, Ratner N. Ling BC, et al. Among authors: wu j. Cancer Cell. 2005 Jan;7(1):65-75. doi: 10.1016/j.ccr.2004.10.016. Cancer Cell. 2005. PMID: 15652750 Free PMC article.

2

Perinatal epidermal growth factor receptor blockade prevents peripheral nerve disruption in a mouse model reminiscent of benign world health organization grade I neurofibroma.

Wu J, Crimmins JT, Monk KR, Williams JP, Fitzgerald ME, Tedesco S, Ratner N. Wu J, et al. Am J Pathol. 2006 May;168(5):1686-96. doi: 10.2353/ajpath.2006.050859. Am J Pathol. 2006. PMID: 16651634 Free PMC article.

3

Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells.

Wu J, Williams JP, Rizvi TA, Kordich JJ, Witte D, Meijer D, Stemmer-Rachamimov AO, Cancelas JA, Ratner N. Wu J, et al. Cancer Cell. 2008 Feb;13(2):105-16. doi: 10.1016/j.ccr.2007.12.027. Cancer Cell. 2008. PMID: 18242511 Free PMC article.

4

Mast cells can contribute to axon-glial dissociation and fibrosis in peripheral nerve.

Monk KR, Wu J, Williams JP, Finney BA, Fitzgerald ME, Filippi MD, Ratner N. Monk KR, et al. Among authors: wu j. Neuron Glia Biol. 2007 Aug;3(3):233-44. doi: 10.1017/S1740925X08000021. Neuron Glia Biol. 2007. PMID: 18634614 Free PMC article.

5

Nf1 mutation expands an EGFR-dependent peripheral nerve progenitor that confers neurofibroma tumorigenic potential.

Williams JP, Wu J, Johansson G, Rizvi TA, Miller SC, Geiger H, Malik P, Li W, Mukouyama YS, Cancelas JA, Ratner N. Williams JP, et al. Among authors: wu j. Cell Stem Cell. 2008 Dec 4;3(6):658-69. doi: 10.1016/j.stem.2008.10.003. Cell Stem Cell. 2008. PMID: 19041782 Free PMC article.

6

Preclincial testing of sorafenib and RAD001 in the Nf(flox/flox) ;DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging.

Wu J, Dombi E, Jousma E, Scott Dunn R, Lindquist D, Schnell BM, Kim MO, Kim A, Widemann BC, Cripe TP, Ratner N. Wu J, et al. Pediatr Blood Cancer. 2012 Feb;58(2):173-80. doi: 10.1002/pbc.23015. Epub 2011 Feb 11. Pediatr Blood Cancer. 2012. PMID: 21319287 Free PMC article.

7

In vivo regulation of TGF-β by R-Ras2 revealed through loss of the RasGAP protein NF1.

Patmore DM, Welch S, Fulkerson PC, Wu J, Choi K, Eaves D, Kordich JJ, Collins MH, Cripe TP, Ratner N. Patmore DM, et al. Among authors: wu j. Cancer Res. 2012 Oct 15;72(20):5317-27. doi: 10.1158/0008-5472.CAN-12-1972. Epub 2012 Aug 23. Cancer Res. 2012. PMID: 22918885 Free PMC article.

8

Neurofibroma-associated macrophages play roles in tumor growth and response to pharmacological inhibition.

Prada CE, Jousma E, Rizvi TA, Wu J, Dunn RS, Mayes DA, Cancelas JA, Dombi E, Kim MO, West BL, Bollag G, Ratner N. Prada CE, et al. Among authors: wu j. Acta Neuropathol. 2013 Jan;125(1):159-68. doi: 10.1007/s00401-012-1056-7. Epub 2012 Oct 26. Acta Neuropathol. 2013. PMID: 23099891 Free PMC article.

9

MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors.

Jessen WJ, Miller SJ, Jousma E, Wu J, Rizvi TA, Brundage ME, Eaves D, Widemann B, Kim MO, Dombi E, Sabo J, Hardiman Dudley A, Niwa-Kawakita M, Page GP, Giovannini M, Aronow BJ, Cripe TP, Ratner N. Jessen WJ, et al. Among authors: wu j. J Clin Invest. 2013 Jan;123(1):340-7. doi: 10.1172/JCI60578. Epub 2012 Dec 10. J Clin Invest. 2013. PMID: 23221341 Free PMC article. Clinical Trial.

10

Preclinical assessments of the MEK inhibitor PD-0325901 in a mouse model of Neurofibromatosis type 1.

Jousma E, Rizvi TA, Wu J, Janhofer D, Dombi E, Dunn RS, Kim MO, Masters AR, Jones DR, Cripe TP, Ratner N. Jousma E, et al. Among authors: wu j. Pediatr Blood Cancer. 2015 Oct;62(10):1709-16. doi: 10.1002/pbc.25546. Epub 2015 Apr 22. Pediatr Blood Cancer. 2015. PMID: 25907661 Free PMC article.

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