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Antiproliferative plant and synthetic polyphenolics are specific inhibitors of vertebrate inositol-1,4,5-trisphosphate 3-kinases and inositol polyphosphate multikinase.
J Biol Chem. 2005 Apr 8;280(14):13229-40. doi: 10.1074/jbc.M500545200. Epub 2005 Jan 19.
J Biol Chem. 2005.
PMID: 15659385
Free article.
The second messenger binding site of inositol 1,4,5-trisphosphate 3-kinase is centered in the catalytic domain and related to the inositol trisphosphate receptor site.
Bertsch U, Deschermeier C, Fanick W, Girkontaite I, Hillemeier K, Johnen H, Weglöhner W, Emmrich F, Mayr GW.
Bertsch U, et al. Among authors: hillemeier k.
J Biol Chem. 2000 Jan 21;275(3):1557-64. doi: 10.1074/jbc.275.3.1557.
J Biol Chem. 2000.
PMID: 10636844
Free article.
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