Poor embryo development in post-ovulatory in vivo-aged mouse oocytes is associated with mitochondrial dysfunction, but mitochondrial transfer from somatic cells is not sufficient for rejuvenation.
Igarashi H, Takahashi T, Abe H, Nakano H, Nakajima O, Nagase S.
Igarashi H, et al.
Hum Reprod. 2016 Oct;31(10):2331-8. doi: 10.1093/humrep/dew203. Epub 2016 Sep 2.
Hum Reprod. 2016.
PMID: 27591230
PARTICIPANTS/MATERIALS, SETTING, METHOD: Superovulated oocytes released from the oviduct at 14 h and 20-24 h post-hCG injection were designated as 'fresh' and 'aged' oocytes, respectively. ...STUDY FUNDING/COMPETING INTERESTS: This study was supported by Grants-in-A …
PARTICIPANTS/MATERIALS, SETTING, METHOD: Superovulated oocytes released from the oviduct at 14 h and 20-24 h post-hCG injectio …