Hashimoto N - Search Results

1

Deletion of Cdkn1b ameliorates hyperglycemia by maintaining compensatory hyperinsulinemia in diabetic mice.

Uchida T, Nakamura T, Hashimoto N, Matsuda T, Kotani K, Sakaue H, Kido Y, Hayashi Y, Nakayama KI, White MF, Kasuga M. Uchida T, et al. Among authors: hashimoto n. Nat Med. 2005 Feb;11(2):175-82. doi: 10.1038/nm1187. Epub 2005 Jan 30. Nat Med. 2005. PMID: 15685168

2

Role of STAT-3 in regulation of hepatic gluconeogenic genes and carbohydrate metabolism in vivo.

Inoue H, Ogawa W, Ozaki M, Haga S, Matsumoto M, Furukawa K, Hashimoto N, Kido Y, Mori T, Sakaue H, Teshigawara K, Jin S, Iguchi H, Hiramatsu R, LeRoith D, Takeda K, Akira S, Kasuga M. Inoue H, et al. Among authors: hashimoto n. Nat Med. 2004 Feb;10(2):168-74. doi: 10.1038/nm980. Epub 2004 Jan 11. Nat Med. 2004. PMID: 14716305

3

PKClambda regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic beta cells.

Hashimoto N, Kido Y, Uchida T, Matsuda T, Suzuki K, Inoue H, Matsumoto M, Ogawa W, Maeda S, Fujihara H, Ueta Y, Uchiyama Y, Akimoto K, Ohno S, Noda T, Kasuga M. Hashimoto N, et al. J Clin Invest. 2005 Jan;115(1):138-45. doi: 10.1172/JCI22232. J Clin Invest. 2005. PMID: 15630453 Free PMC article.

4

Ablation of PDK1 in pancreatic beta cells induces diabetes as a result of loss of beta cell mass.

Hashimoto N, Kido Y, Uchida T, Asahara S, Shigeyama Y, Matsuda T, Takeda A, Tsuchihashi D, Nishizawa A, Ogawa W, Fujimoto Y, Okamura H, Arden KC, Herrera PL, Noda T, Kasuga M. Hashimoto N, et al. Nat Genet. 2006 May;38(5):589-93. doi: 10.1038/ng1774. Epub 2006 Apr 23. Nat Genet. 2006. PMID: 16642023

5

Biphasic response of pancreatic beta-cell mass to ablation of tuberous sclerosis complex 2 in mice.

Shigeyama Y, Kobayashi T, Kido Y, Hashimoto N, Asahara S, Matsuda T, Takeda A, Inoue T, Shibutani Y, Koyanagi M, Uchida T, Inoue M, Hino O, Kasuga M, Noda T. Shigeyama Y, et al. Among authors: hashimoto n. Mol Cell Biol. 2008 May;28(9):2971-9. doi: 10.1128/MCB.01695-07. Epub 2008 Mar 3. Mol Cell Biol. 2008. PMID: 18316403 Free PMC article.

6

The kinase PDK1 integrates T cell antigen receptor and CD28 coreceptor signaling to induce NF-kappaB and activate T cells.

Park SG, Schulze-Luehrman J, Hayden MS, Hashimoto N, Ogawa W, Kasuga M, Ghosh S. Park SG, et al. Among authors: hashimoto n. Nat Immunol. 2009 Feb;10(2):158-66. doi: 10.1038/ni.1687. Epub 2009 Jan 4. Nat Immunol. 2009. PMID: 19122654 Free PMC article.

7

Pancreatic beta cell mass preserved in heterozygous PDK1 knockout mice.

Takeda A, Kido Y, Hashimoto N, Noda T, Kasuga M. Takeda A, et al. Among authors: hashimoto n. Kobe J Med Sci. 2008 Sep 5;54(3):E183-90. Kobe J Med Sci. 2008. PMID: 19246967 Free article.

8

Ablation of C/EBPbeta alleviates ER stress and pancreatic beta cell failure through the GRP78 chaperone in mice.

Matsuda T, Kido Y, Asahara S, Kaisho T, Tanaka T, Hashimoto N, Shigeyama Y, Takeda A, Inoue T, Shibutani Y, Koyanagi M, Hosooka T, Matsumoto M, Inoue H, Uchida T, Koike M, Uchiyama Y, Akira S, Kasuga M. Matsuda T, et al. Among authors: hashimoto n. J Clin Invest. 2010 Jan;120(1):115-26. doi: 10.1172/JCI39721. Epub 2009 Dec 1. J Clin Invest. 2010. PMID: 19955657 Free PMC article.

9

Ablation of TSC2 enhances insulin secretion by increasing the number of mitochondria through activation of mTORC1.

Koyanagi M, Asahara S, Matsuda T, Hashimoto N, Shigeyama Y, Shibutani Y, Kanno A, Fuchita M, Mikami T, Hosooka T, Inoue H, Matsumoto M, Koike M, Uchiyama Y, Noda T, Seino S, Kasuga M, Kido Y. Koyanagi M, et al. Among authors: hashimoto n. PLoS One. 2011;6(8):e23238. doi: 10.1371/journal.pone.0023238. Epub 2011 Aug 19. PLoS One. 2011. PMID: 21886784 Free PMC article.

10

DPP4 inhibitor vildagliptin preserves β-cell mass through amelioration of endoplasmic reticulum stress in C/EBPB transgenic mice.

Shimizu S, Hosooka T, Matsuda T, Asahara S, Koyanagi-Kimura M, Kanno A, Bartolome A, Etoh H, Fuchita M, Teruyama K, Takahashi H, Inoue H, Mieda Y, Hashimoto N, Seino S, Kido Y. Shimizu S, et al. Among authors: hashimoto n. J Mol Endocrinol. 2012 Aug 30;49(2):125-35. doi: 10.1530/JME-12-0039. Print 2012 Oct. J Mol Endocrinol. 2012. PMID: 22822047

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