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Azaspirane (N-N-diethyl-8,8-dipropyl-2-azaspiro [4.5] decane-2-propanamine) inhibits human multiple myeloma cell growth in the bone marrow milieu in vitro and in vivo.
Hamasaki M, Hideshima T, Tassone P, Neri P, Ishitsuka K, Yasui H, Shiraishi N, Raje N, Kumar S, Picker DH, Jacob GS, Richardson PG, Munshi NC, Anderson KC. Hamasaki M, et al. Among authors: jacob gs. Blood. 2005 Jun 1;105(11):4470-6. doi: 10.1182/blood-2004-09-3794. Epub 2005 Feb 10. Blood. 2005. PMID: 15705788 Free PMC article.
Biological pathways and in vivo antitumor activity induced by Atiprimod in myeloma.
Neri P, Tassone P, Shammas M, Yasui H, Schipani E, Batchu RB, Blotta S, Prabhala R, Catley L, Hamasaki M, Hideshima T, Chauhan D, Jacob GS, Picker D, Venuta S, Anderson KC, Munshi NC. Neri P, et al. Among authors: jacob gs. Leukemia. 2007 Dec;21(12):2519-26. doi: 10.1038/sj.leu.2404912. Epub 2007 Sep 20. Leukemia. 2007. PMID: 17882285
A clinically relevant SCID-hu in vivo model of human multiple myeloma.
Tassone P, Neri P, Carrasco DR, Burger R, Goldmacher VS, Fram R, Munshi V, Shammas MA, Catley L, Jacob GS, Venuta S, Anderson KC, Munshi NC. Tassone P, et al. Among authors: jacob gs. Blood. 2005 Jul 15;106(2):713-6. doi: 10.1182/blood-2005-01-0373. Epub 2005 Apr 7. Blood. 2005. PMID: 15817674 Free PMC article.
Plecanatide and dolcanatide, novel guanylate cyclase-C agonists, ameliorate gastrointestinal inflammation in experimental models of murine colitis.
Shailubhai K, Palejwala V, Arjunan KP, Saykhedkar S, Nefsky B, Foss JA, Comiskey S, Jacob GS, Plevy SE. Shailubhai K, et al. Among authors: jacob gs. World J Gastrointest Pharmacol Ther. 2015 Nov 6;6(4):213-22. doi: 10.4292/wjgpt.v6.i4.213. World J Gastrointest Pharmacol Ther. 2015. PMID: 26558155 Free PMC article.
59 results