Fine RL - Search Results

1

The role of alpha-helical structure in p53 peptides as a determinant for their mechanism of cell death: necrosis versus apoptosis.

Rosal R, Brandt-Rauf P, Pincus MR, Wang H, Mao Y, Li Y, Fine RL. Rosal R, et al. Among authors: fine rl. Adv Drug Deliv Rev. 2005 Feb 28;57(4):653-60. doi: 10.1016/j.addr.2004.10.008. Epub 2005 Jan 8. Adv Drug Deliv Rev. 2005. PMID: 15722169 Review.

2

Conformational and molecular basis for induction of apoptosis by a p53 C-terminal peptide in human cancer cells.

Kim AL, Raffo AJ, Brandt-Rauf PW, Pincus MR, Monaco R, Abarzua P, Fine RL. Kim AL, et al. Among authors: fine rl. J Biol Chem. 1999 Dec 3;274(49):34924-31. doi: 10.1074/jbc.274.49.34924. J Biol Chem. 1999. PMID: 10574967 Free article.

3

Formation of nuclear Bax/p53 complexes is associated with chemotherapy induced apoptosis.

Raffo AJ, Kim AL, Fine RL. Raffo AJ, et al. Among authors: fine rl. Oncogene. 2000 Dec 14;19(54):6216-28. doi: 10.1038/sj.onc.1203995. Oncogene. 2000. PMID: 11175336

4

Peptides from the amino terminal mdm-2-binding domain of p53, designed from conformational analysis, are selectively cytotoxic to transformed cells.

Kanovsky M, Raffo A, Drew L, Rosal R, Do T, Friedman FK, Rubinstein P, Visser J, Robinson R, Brandt-Rauf PW, Michl J, Fine RL, Pincus MR. Kanovsky M, et al. Among authors: fine rl. Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12438-43. doi: 10.1073/pnas.211280698. Epub 2001 Oct 16. Proc Natl Acad Sci U S A. 2001. PMID: 11606716 Free PMC article.

5

Correlation between hydrophobic properties and efficiency of carrier-mediated membrane transduction and apoptosis of a p53 C-terminal peptide.

Li Y, Rosal RV, Brandt-Rauf PW, Fine RL. Li Y, et al. Among authors: fine rl. Biochem Biophys Res Commun. 2002 Nov 1;298(3):439-49. doi: 10.1016/s0006-291x(02)02470-1. Biochem Biophys Res Commun. 2002. PMID: 12413961

6

Preferential induction of necrosis in human breast cancer cells by a p53 peptide derived from the MDM2 binding site.

Do TN, Rosal RV, Drew L, Raffo AJ, Michl J, Pincus MR, Friedman FK, Petrylak DP, Cassai N, Szmulewicz J, Sidhu G, Fine RL, Brandt-Rauf PW. Do TN, et al. Among authors: fine rl. Oncogene. 2003 Mar 13;22(10):1431-44. doi: 10.1038/sj.onc.1206258. Oncogene. 2003. PMID: 12629507

7

Fas-mediated apoptosis is dependent on wild-type p53 status in human cancer cells expressing a temperature-sensitive p53 mutant alanine-143.

Li Y, Raffo AJ, Drew L, Mao Y, Tran A, Petrylak DP, Fine RL. Li Y, et al. Among authors: fine rl. Cancer Res. 2003 Apr 1;63(7):1527-33. Cancer Res. 2003. PMID: 12670900

8

NMR solution structure of a peptide from the mdm-2 binding domain of the p53 protein that is selectively cytotoxic to cancer cells.

Rosal R, Pincus MR, Brandt-Rauf PW, Fine RL, Michl J, Wang H. Rosal R, et al. Among authors: fine rl. Biochemistry. 2004 Feb 24;43(7):1854-61. doi: 10.1021/bi035718g. Biochemistry. 2004. PMID: 14967026

9

Computational protein chemistry of p53 and p53 peptides.

Brandt-Rauf PW, Rosal RV, Fine RL, Pincus MR. Brandt-Rauf PW, et al. Among authors: fine rl. Front Biosci. 2004 Sep 1;9:2778-87. doi: 10.2741/1435. Front Biosci. 2004. PMID: 15353313 Review.

10

Selective induction of apoptosis through the FADD/caspase-8 pathway by a p53 c-terminal peptide in human pre-malignant and malignant cells.

Li Y, Mao Y, Rosal RV, Dinnen RD, Williams AC, Brandt-Rauf PW, Fine RL. Li Y, et al. Among authors: fine rl. Int J Cancer. 2005 May 20;115(1):55-64. doi: 10.1002/ijc.20838. Int J Cancer. 2005. PMID: 15645452

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