Murray SF - Search Results

1

Spinal distribution and metabolism of 2'-O-(2-methoxyethyl)-modified oligonucleotides after intrathecal administration in rats.

Butler M, Hayes CS, Chappell A, Murray SF, Yaksh TL, Hua XY. Butler M, et al. Among authors: murray sf. Neuroscience. 2005;131(3):705-15. doi: 10.1016/j.neuroscience.2004.11.038. Neuroscience. 2005. PMID: 15730875

2

Phosphorothioate oligodeoxynucleotides distribute similarly in class A scavenger receptor knockout and wild-type mice.

Butler M, Crooke RM, Graham MJ, Lemonidis KM, Lougheed M, Murray SF, Witchell D, Steinbrecher U, Bennett CF. Butler M, et al. Among authors: murray sf. J Pharmacol Exp Ther. 2000 Feb;292(2):489-96. J Pharmacol Exp Ther. 2000. PMID: 10640284

3

Specific inhibition of PTEN expression reverses hyperglycemia in diabetic mice.

Butler M, McKay RA, Popoff IJ, Gaarde WA, Witchell D, Murray SF, Dean NM, Bhanot S, Monia BP. Butler M, et al. Among authors: murray sf. Diabetes. 2002 Apr;51(4):1028-34. doi: 10.2337/diabetes.51.4.1028. Diabetes. 2002. PMID: 11916922

4

Inhibition of spinal protein kinase Calpha expression by an antisense oligonucleotide attenuates morphine infusion-induced tolerance.

Hua XY, Moore A, Malkmus S, Murray SF, Dean N, Yaksh TL, Butler M. Hua XY, et al. Among authors: murray sf. Neuroscience. 2002;113(1):99-107. doi: 10.1016/s0306-4522(02)00157-4. Neuroscience. 2002. PMID: 12123688

5

Antisense oligonucleotide blockade of tumor necrosis factor-alpha in two murine models of colitis.

Myers KJ, Murthy S, Flanigan A, Witchell DR, Butler M, Murray S, Siwkowski A, Goodfellow D, Madsen K, Baker B. Myers KJ, et al. J Pharmacol Exp Ther. 2003 Jan;304(1):411-24. doi: 10.1124/jpet.102.040329. J Pharmacol Exp Ther. 2003. PMID: 12490618

6

Inhibition of protein tyrosine phosphatase-1B with antisense oligonucleotides improves insulin sensitivity and increases adiponectin concentrations in monkeys.

Swarbrick MM, Havel PJ, Levin AA, Bremer AA, Stanhope KL, Butler M, Booten SL, Graham JL, McKay RA, Murray SF, Watts LM, Monia BP, Bhanot S. Swarbrick MM, et al. Among authors: murray sf. Endocrinology. 2009 Apr;150(4):1670-9. doi: 10.1210/en.2008-0885. Epub 2009 Jan 22. Endocrinology. 2009. PMID: 19164474 Free PMC article.

7

TricycloDNA-modified oligo-2'-deoxyribonucleotides reduce scavenger receptor B1 mRNA in hepatic and extra-hepatic tissues--a comparative study of oligonucleotide length, design and chemistry.

Murray S, Ittig D, Koller E, Berdeja A, Chappell A, Prakash TP, Norrbom M, Swayze EE, Leumann CJ, Seth PP. Murray S, et al. Nucleic Acids Res. 2012 Jul;40(13):6135-43. doi: 10.1093/nar/gks273. Epub 2012 Mar 30. Nucleic Acids Res. 2012. PMID: 22467214 Free PMC article.

8

Single-stranded siRNAs activate RNAi in animals.

Lima WF, Prakash TP, Murray HM, Kinberger GA, Li W, Chappell AE, Li CS, Murray SF, Gaus H, Seth PP, Swayze EE, Crooke ST. Lima WF, et al. Among authors: murray sf, murray hm. Cell. 2012 Aug 31;150(5):883-94. doi: 10.1016/j.cell.2012.08.014. Cell. 2012. PMID: 22939618 Free article.

9

Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency 10-fold in mice.

Prakash TP, Graham MJ, Yu J, Carty R, Low A, Chappell A, Schmidt K, Zhao C, Aghajan M, Murray HF, Riney S, Booten SL, Murray SF, Gaus H, Crosby J, Lima WF, Guo S, Monia BP, Swayze EE, Seth PP. Prakash TP, et al. Among authors: murray hf, murray sf. Nucleic Acids Res. 2014 Jul;42(13):8796-807. doi: 10.1093/nar/gku531. Epub 2014 Jul 3. Nucleic Acids Res. 2014. PMID: 24992960 Free PMC article.

10

Comprehensive Structure-Activity Relationship of Triantennary N-Acetylgalactosamine Conjugated Antisense Oligonucleotides for Targeted Delivery to Hepatocytes.

Prakash TP, Yu J, Migawa MT, Kinberger GA, Wan WB, Østergaard ME, Carty RL, Vasquez G, Low A, Chappell A, Schmidt K, Aghajan M, Crosby J, Murray HM, Booten SL, Hsiao J, Soriano A, Machemer T, Cauntay P, Burel SA, Murray SF, Gaus H, Graham MJ, Swayze EE, Seth PP. Prakash TP, et al. Among authors: murray sf, murray hm. J Med Chem. 2016 Mar 24;59(6):2718-33. doi: 10.1021/acs.jmedchem.5b01948. Epub 2016 Mar 9. J Med Chem. 2016. PMID: 26914862

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