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464 results

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Page 1
Variation in the human TP53 gene affects old age survival and cancer mortality.
van Heemst D, Mooijaart SP, Beekman M, Schreuder J, de Craen AJ, Brandt BW, Slagboom PE, Westendorp RG; Long Life study group. van Heemst D, et al. Among authors: de craen aj. Exp Gerontol. 2005 Jan-Feb;40(1-2):11-5. doi: 10.1016/j.exger.2004.10.001. Exp Gerontol. 2005. PMID: 15732191 Review.
Plasma levels of apolipoprotein E and risk of stroke in old age.
van Vliet P, Mooijaart SP, de Craen AJ, Rensen PC, van Heemst D, Westendorp RG. van Vliet P, et al. Among authors: de craen aj. Ann N Y Acad Sci. 2007 Apr;1100:140-7. doi: 10.1196/annals.1395.012. Ann N Y Acad Sci. 2007. PMID: 17460172
Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: cross sectional and longitudinal studies.
Soerensen M, Dato S, Tan Q, Thinggaard M, Kleindorp R, Beekman M, Jacobsen R, Suchiman HE, de Craen AJ, Westendorp RG, Schreiber S, Stevnsner T, Bohr VA, Slagboom PE, Nebel A, Vaupel JW, Christensen K, McGue M, Christiansen L. Soerensen M, et al. Among authors: de craen aj. Exp Gerontol. 2012 May;47(5):379-87. doi: 10.1016/j.exger.2012.02.010. Epub 2012 Mar 3. Exp Gerontol. 2012. PMID: 22406557 Free PMC article.
Renal function in familial longevity: the Leiden Longevity Study.
de Goeij MC, Halbesma N, Dekker FW, Wijsman CA, van Heemst D, Maier AB, Mooijaart SP, Slagboom PE, Westendorp RG, de Craen AJ. de Goeij MC, et al. Among authors: de craen aj. Exp Gerontol. 2014 Mar;51:65-70. doi: 10.1016/j.exger.2013.12.012. Epub 2014 Jan 2. Exp Gerontol. 2014. PMID: 24389060
Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited.
Deelen J, Beekman M, Uh HW, Helmer Q, Kuningas M, Christiansen L, Kremer D, van der Breggen R, Suchiman HE, Lakenberg N, van den Akker EB, Passtoors WM, Tiemeier H, van Heemst D, de Craen AJ, Rivadeneira F, de Geus EJ, Perola M, van der Ouderaa FJ, Gunn DA, Boomsma DI, Uitterlinden AG, Christensen K, van Duijn CM, Heijmans BT, Houwing-Duistermaat JJ, Westendorp RG, Slagboom PE. Deelen J, et al. Among authors: de craen aj, de geus ej. Aging Cell. 2011 Aug;10(4):686-98. doi: 10.1111/j.1474-9726.2011.00705.x. Epub 2011 May 6. Aging Cell. 2011. PMID: 21418511 Free PMC article.
Low serum free triiodothyronine levels mark familial longevity: the Leiden Longevity Study.
Rozing MP, Westendorp RG, de Craen AJ, Frölich M, Heijmans BT, Beekman M, Wijsman C, Mooijaart SP, Blauw GJ, Slagboom PE, van Heemst D; Leiden Longevity Study (LLS) Group. Rozing MP, et al. Among authors: de craen aj. J Gerontol A Biol Sci Med Sci. 2010 Apr;65(4):365-8. doi: 10.1093/gerona/glp200. Epub 2009 Dec 16. J Gerontol A Biol Sci Med Sci. 2010. PMID: 20018826
Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.
Deelen J, Beekman M, Uh HW, Broer L, Ayers KL, Tan Q, Kamatani Y, Bennet AM, Tamm R, Trompet S, Guðbjartsson DF, Flachsbart F, Rose G, Viktorin A, Fischer K, Nygaard M, Cordell HJ, Crocco P, van den Akker EB, Böhringer S, Helmer Q, Nelson CP, Saunders GI, Alver M, Andersen-Ranberg K, Breen ME, van der Breggen R, Caliebe A, Capri M, Cevenini E, Collerton JC, Dato S, Davies K, Ford I, Gampe J, Garagnani P, de Geus EJ, Harrow J, van Heemst D, Heijmans BT, Heinsen FA, Hottenga JJ, Hofman A, Jeune B, Jonsson PV, Lathrop M, Lechner D, Martin-Ruiz C, Mcnerlan SE, Mihailov E, Montesanto A, Mooijaart SP, Murphy A, Nohr EA, Paternoster L, Postmus I, Rivadeneira F, Ross OA, Salvioli S, Sattar N, Schreiber S, Stefánsson H, Stott DJ, Tiemeier H, Uitterlinden AG, Westendorp RG, Willemsen G, Samani NJ, Galan P, Sørensen TI, Boomsma DI, Jukema JW, Rea IM, Passarino G, de Craen AJ, Christensen K, Nebel A, Stefánsson K, Metspalu A, Magnusson P, Blanché H, Christiansen L, Kirkwood TB, van Duijn CM, Franceschi C, Houwing-Duistermaat JJ, Slagboom PE. Deelen J, et al. Among authors: de craen aj, de geus ej. Hum Mol Genet. 2014 Aug 15;23(16):4420-32. doi: 10.1093/hmg/ddu139. Epub 2014 Mar 31. Hum Mol Genet. 2014. PMID: 24688116 Free PMC article.
464 results