Lorenzen A - Search Results

1

A "locked-on," constitutively active mutant of the adenosine A1 receptor.

de Ligt RA, Rivkees SA, Lorenzen A, Leurs R, IJzerman AP. de Ligt RA, et al. Among authors: lorenzen a. Eur J Pharmacol. 2005 Mar 7;510(1-2):1-8. doi: 10.1016/j.ejphar.2005.01.007. Eur J Pharmacol. 2005. PMID: 15740718

2

Synthesis and biological evaluation of disubstituted N6-cyclopentyladenine analogues: the search for a neutral antagonist with high affinity for the adenosine A1 receptor.

de Ligt RA, van der Klein PA, von Frijtag Drabbe Künzel JK, Lorenzen A, Ait El Maate F, Fujikawa S, van Westhoven R, van den Hoven T, Brussee J, IJzerman AP. de Ligt RA, et al. Among authors: lorenzen a. Bioorg Med Chem. 2004 Jan 2;12(1):139-49. doi: 10.1016/j.bmc.2003.10.023. Bioorg Med Chem. 2004. PMID: 14697779

3

Allosteric modulation and constitutive activity of fusion proteins between the adenosine A1 receptor and different 351Cys-mutated Gi alpha-subunits.

Klaasse E, de Ligt RA, Roerink SF, Lorenzen A, Milligan G, Leurs R, IJzerman AP. Klaasse E, et al. Among authors: lorenzen a. Eur J Pharmacol. 2004 Sep 19;499(1-2):91-8. doi: 10.1016/j.ejphar.2004.07.108. Eur J Pharmacol. 2004. PMID: 15363955

4

Biological activities of N6,C8-disubstituted adenosine derivatives as partial agonists at rat brain adenosine A1 receptors.

Lorenzen A, Sebastião AM, Sellink A, Vogt H, Schwabe U, Ribeiro JA, IJzerman AP. Lorenzen A, et al. Eur J Pharmacol. 1997 Sep 10;334(2-3):299-307. doi: 10.1016/s0014-2999(97)01193-x. Eur J Pharmacol. 1997. PMID: 9369361

5

5'-substituted adenosine analogs as new high-affinity partial agonists for the adenosine A1 receptor.

van der Wenden EM, Carnielli M, Roelen HC, Lorenzen A, von Frijtag Drabbe Künzel JK, IJzerman AP. van der Wenden EM, et al. Among authors: lorenzen a. J Med Chem. 1998 Jan 1;41(1):102-8. doi: 10.1021/jm970508l. J Med Chem. 1998. PMID: 9438026

6

N6,5'-Disubstituted adenosine derivatives as partial agonists for the human adenosine A3 receptor.

van Tilburg EW, von Frijtag Drabbe Künzel J, de Groote M, Vollinga RC, Lorenzen A, IJzerman AP. van Tilburg EW, et al. Among authors: lorenzen a. J Med Chem. 1999 Apr 22;42(8):1393-400. doi: 10.1021/jm981090+. J Med Chem. 1999. PMID: 10212125

7

5'-O-alkyl ethers of N,2-substituted adenosine derivatives: partial agonists for the adenosine A1 and A3 receptors.

van Tilburg EW, van der Klein PA, von Frijtag Drabbe Künzel J, de Groote M, Stannek C, Lorenzen A, IJzerman AP. van Tilburg EW, et al. Among authors: lorenzen a. J Med Chem. 2001 Aug 30;44(18):2966-75. doi: 10.1021/jm001114o. J Med Chem. 2001. PMID: 11520205

8

Pyrazole derivatives as partial agonists for the nicotinic acid receptor.

van Herk T, Brussee J, van den Nieuwendijk AM, van der Klein PA, IJzerman AP, Stannek C, Burmeister A, Lorenzen A. van Herk T, et al. Among authors: lorenzen a. J Med Chem. 2003 Aug 28;46(18):3945-51. doi: 10.1021/jm030888c. J Med Chem. 2003. PMID: 12930155

9

N-cycloalkyl derivatives of adenosine and 1-deazaadenosine as agonists and partial agonists of the A(1) adenosine receptor.

Vittori S, Lorenzen A, Stannek C, Costanzi S, Volpini R, IJzerman AP, Kunzel JK, Cristalli G. Vittori S, et al. Among authors: lorenzen a. J Med Chem. 2000 Jan 27;43(2):250-60. doi: 10.1021/jm9911231. J Med Chem. 2000. PMID: 10649980

10

Affinity of central adenosine A1 receptors is decreased in spontaneously hypertensive rats.

Matias A, Zimmer FJ, Lorenzen A, Keil R, Schwabe U. Matias A, et al. Among authors: lorenzen a. Eur J Pharmacol. 1993 Feb 15;244(3):223-30. doi: 10.1016/0922-4106(93)90147-2. Eur J Pharmacol. 1993. PMID: 8458399

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