Cancelas JA - Search Results

1

Rac2-deficient hematopoietic stem cells show defective interaction with the hematopoietic microenvironment and long-term engraftment failure.

Jansen M, Yang FC, Cancelas JA, Bailey JR, Williams DA. Jansen M, et al. Among authors: cancelas ja. Stem Cells. 2005 Mar;23(3):335-46. doi: 10.1634/stemcells.2004-0216. Stem Cells. 2005. PMID: 15749928

2

Hematopoietic cell regulation by Rac1 and Rac2 guanosine triphosphatases.

Gu Y, Filippi MD, Cancelas JA, Siefring JE, Williams EP, Jasti AC, Harris CE, Lee AW, Prabhakar R, Atkinson SJ, Kwiatkowski DJ, Williams DA. Gu Y, et al. Among authors: cancelas ja. Science. 2003 Oct 17;302(5644):445-9. doi: 10.1126/science.1088485. Science. 2003. PMID: 14564009

3

Rac GTPases differentially integrate signals regulating hematopoietic stem cell localization.

Cancelas JA, Lee AW, Prabhakar R, Stringer KF, Zheng Y, Williams DA. Cancelas JA, et al. Nat Med. 2005 Aug;11(8):886-91. doi: 10.1038/nm1274. Epub 2005 Jul 17. Nat Med. 2005. PMID: 16025125

4

A rapid method for retrovirus-mediated identification of complementation groups in Fanconi anemia patients.

Chandra S, Levran O, Jurickova I, Maas C, Kapur R, Schindler D, Henry R, Milton K, Batish SD, Cancelas JA, Hanenberg H, Auerbach AD, Williams DA. Chandra S, et al. Among authors: cancelas ja. Mol Ther. 2005 Nov;12(5):976-84. doi: 10.1016/j.ymthe.2005.04.021. Epub 2005 Aug 9. Mol Ther. 2005. PMID: 16084127 Free article.

5

The FIP1L1-PDGFRA fusion gene cooperates with IL-5 to induce murine hypereosinophilic syndrome (HES)/chronic eosinophilic leukemia (CEL)-like disease.

Yamada Y, Rothenberg ME, Lee AW, Akei HS, Brandt EB, Williams DA, Cancelas JA. Yamada Y, et al. Among authors: cancelas ja. Blood. 2006 May 15;107(10):4071-9. doi: 10.1182/blood-2005-08-3153. Epub 2006 Jan 17. Blood. 2006. PMID: 16418325 Free PMC article.

6

Rational design and applications of a Rac GTPase-specific small molecule inhibitor.

Akbar H, Cancelas J, Williams DA, Zheng J, Zheng Y. Akbar H, et al. Methods Enzymol. 2006;406:554-65. doi: 10.1016/S0076-6879(06)06043-5. Methods Enzymol. 2006. PMID: 16472687

7

Stem cell mobilization by beta2-agonists.

Cancelas JA, Williams DA. Cancelas JA, et al. Nat Med. 2006 Mar;12(3):278-9. doi: 10.1038/nm0306-278. Nat Med. 2006. PMID: 16520770 No abstract available.

8

Bone marrow connexin-43 expression is critical for hematopoietic regeneration after chemotherapy.

Presley CA, Lee AW, Kastl B, Igbinosa I, Yamada Y, Fishman GI, Gutstein DE, Cancelas JA. Presley CA, et al. Among authors: cancelas ja. Cell Commun Adhes. 2005 Jul-Dec;12(5-6):307-17. doi: 10.1080/15419060500514200. Cell Commun Adhes. 2005. PMID: 16531325 Free article.

9

Inhibition of RhoA GTPase activity enhances hematopoietic stem and progenitor cell proliferation and engraftment.

Ghiaur G, Lee A, Bailey J, Cancelas JA, Zheng Y, Williams DA. Ghiaur G, et al. Among authors: cancelas ja. Blood. 2006 Sep 15;108(6):2087-94. doi: 10.1182/blood-2006-02-001560. Epub 2006 May 18. Blood. 2006. PMID: 16709932 Free article.

10

Structure-function based design of small molecule inhibitors targeting Rho family GTPases.

Nassar N, Cancelas J, Zheng J, Williams DA, Zheng Y. Nassar N, et al. Curr Top Med Chem. 2006;6(11):1109-16. doi: 10.2174/156802606777812095. Curr Top Med Chem. 2006. PMID: 16842149 Review.

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