Hatakeyama S - Search Results

1

Measurement and characterization of C-3 epimerization activity toward vitamin D3.

Kamao M, Hatakeyama S, Sakaki T, Sawada N, Inouye K, Kubodera N, Reddy GS, Okano T. Kamao M, et al. Among authors: hatakeyama s. Arch Biochem Biophys. 2005 Apr 1;436(1):196-205. doi: 10.1016/j.abb.2005.01.017. Arch Biochem Biophys. 2005. PMID: 15752725

2

Two novel metabolic pathways of 22-oxacalcitriol (OCT). C-25 dehydration and C-3 epimerization and biological activities of novel OCT metabolites.

Kamao M, Tatematsu S, Hatakeyama S, Ozono K, Kubodera N, Reddy GS, Okano T. Kamao M, et al. Among authors: hatakeyama s. J Biol Chem. 2003 Jan 17;278(3):1463-71. doi: 10.1074/jbc.M203773200. Epub 2002 Nov 1. J Biol Chem. 2003. PMID: 12417596 Free article.

3

C-3 epimerization of vitamin D3 metabolites and further metabolism of C-3 epimers: 25-hydroxyvitamin D3 is metabolized to 3-epi-25-hydroxyvitamin D3 and subsequently metabolized through C-1alpha or C-24 hydroxylation.

Kamao M, Tatematsu S, Hatakeyama S, Sakaki T, Sawada N, Inouye K, Ozono K, Kubodera N, Reddy GS, Okano T. Kamao M, et al. Among authors: hatakeyama s. J Biol Chem. 2004 Apr 16;279(16):15897-907. doi: 10.1074/jbc.M311473200. Epub 2004 Feb 2. J Biol Chem. 2004. PMID: 14757768 Free article.

4

Cell specificity and properties of the C-3 epimerization of Vitamin D3 metabolites.

Kamao M, Tatematsu S, Sawada N, Sakaki T, Hatakeyama S, Kubodera N, Okano T. Kamao M, et al. Among authors: hatakeyama s. J Steroid Biochem Mol Biol. 2004 May;89-90(1-5):39-42. doi: 10.1016/j.jsbmb.2004.03.048. J Steroid Biochem Mol Biol. 2004. PMID: 15225744

5

Isolation, identification and biological activity of 24R,25-dihydroxy-3-epi-vitamin D3: a novel metabolite of 24R,25-dihydroxyvitamin D3 produced in rat osteosarcoma cells (UMR 106).

Kamao M, Tatematsu S, Reddy GS, Hatakeyama S, Sugiura M, Ohashi N, Kubodera N, Okano T. Kamao M, et al. Among authors: hatakeyama s. J Nutr Sci Vitaminol (Tokyo). 2001 Apr;47(2):108-15. doi: 10.3177/jnsv.47.108. J Nutr Sci Vitaminol (Tokyo). 2001. PMID: 11508700

6

Synthesis and biological evaluation of a 3-positon epimer of 1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)vitamin D3 (ED-71).

Hatakeyama S, Nagashima S, Imai N, Takahashi K, Ishihara J, Sugita A, Nihei T, Saito H, Takahashi F, Kubodera N. Hatakeyama S, et al. J Steroid Biochem Mol Biol. 2007 Mar;103(3-5):222-6. doi: 10.1016/j.jsbmb.2006.12.025. Epub 2007 Jan 5. J Steroid Biochem Mol Biol. 2007. PMID: 17207991

7

Synthesis of all possible A-ring diastereomers at the 1- and 3-positions of 1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)vitamin D3 (ED-71) using C2-symmetrical epoxide as a common starting material.

Kubodera N, Hatakeyama S. Kubodera N, et al. Among authors: hatakeyama s. Anticancer Res. 2009 Sep;29(9):3571-8. Anticancer Res. 2009. PMID: 19667150 Free article.

8

Novel metabolism of 1 alpha,25-dihydroxyvitamin D3 with C24-C25 bond cleavage catalyzed by human CYP24A1.

Sawada N, Kusudo T, Sakaki T, Hatakeyama S, Hanada M, Abe D, Kamao M, Okano T, Ohta M, Inouye K. Sawada N, et al. Among authors: hatakeyama s. Biochemistry. 2004 Apr 20;43(15):4530-7. doi: 10.1021/bi030207f. Biochemistry. 2004. PMID: 15078099

9

Synthesis of putative metabolites of 1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)vitamin D(3) (ED-71).

Ono Y, Watanabe H, Taira I, Takahashi K, Ishihara J, Hatakeyama S, Kubodera N. Ono Y, et al. Among authors: hatakeyama s. Steroids. 2006 Jul;71(7):529-40. doi: 10.1016/j.steroids.2005.11.001. Epub 2006 Apr 25. Steroids. 2006. PMID: 16635499

10

Synthesis and evaluation of a 3-position diastereomer of 1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)vitamin D3 (ED-71).

Hatakeyama S, Nagashima S, Imai N, Takahashi K, Ishihara J, Sugita A, Nihei T, Saito H, Takahashi F, Kubodera N. Hatakeyama S, et al. Bioorg Med Chem. 2006 Dec 1;14(23):8050-6. doi: 10.1016/j.bmc.2006.07.039. Bioorg Med Chem. 2006. PMID: 16908172

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