Skoko J - Search Results

1

The benzo[c]phenanthridine alkaloid, sanguinarine, is a selective, cell-active inhibitor of mitogen-activated protein kinase phosphatase-1.

Vogt A, Tamewitz A, Skoko J, Sikorski RP, Giuliano KA, Lazo JS. Vogt A, et al. Among authors: skoko j. J Biol Chem. 2005 May 13;280(19):19078-86. doi: 10.1074/jbc.M501467200. Epub 2005 Mar 7. J Biol Chem. 2005. PMID: 15753082 Free article.

2

22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid beta secretion.

Koldamova RP, Lefterov IM, Ikonomovic MD, Skoko J, Lefterov PI, Isanski BA, DeKosky ST, Lazo JS. Koldamova RP, et al. Among authors: skoko j. J Biol Chem. 2003 Apr 11;278(15):13244-56. doi: 10.1074/jbc.M300044200. Epub 2003 Jan 22. J Biol Chem. 2003. PMID: 12547833 Free article.

3

MKP-8, a novel MAPK phosphatase that inhibits p38 kinase.

Vasudevan SA, Skoko J, Wang K, Burlingame SM, Patel PN, Lazo JS, Nuchtern JG, Yang J. Vasudevan SA, et al. Among authors: skoko j. Biochem Biophys Res Commun. 2005 May 6;330(2):511-8. doi: 10.1016/j.bbrc.2005.03.028. Biochem Biophys Res Commun. 2005. PMID: 15796912

4

Novel benzofuran inhibitors of human mitogen-activated protein kinase phosphatase-1.

Lazo JS, Nunes R, Skoko JJ, Queiroz de Oliveira PE, Vogt A, Wipf P. Lazo JS, et al. Among authors: skoko jj. Bioorg Med Chem. 2006 Aug 15;14(16):5643-50. doi: 10.1016/j.bmc.2006.04.036. Epub 2006 May 15. Bioorg Med Chem. 2006. PMID: 16698271

5

Biological evaluation of newly synthesized quinoline-5,8-quinones as Cdc25B inhibitors.

Cossy J, Belotti D, Brisson M, Skoko JJ, Wipf P, Lazo JS. Cossy J, et al. Among authors: skoko jj. Bioorg Med Chem. 2006 Sep 15;14(18):6283-7. doi: 10.1016/j.bmc.2006.05.053. Epub 2006 Jun 16. Bioorg Med Chem. 2006. PMID: 16782352

6

Structurally unique inhibitors of human mitogen-activated protein kinase phosphatase-1 identified in a pyrrole carboxamide library.

Lazo JS, Skoko JJ, Werner S, Mitasev B, Bakan A, Koizumi F, Yellow-Duke A, Bahar I, Brummond KM. Lazo JS, et al. Among authors: skoko jj. J Pharmacol Exp Ther. 2007 Sep;322(3):940-7. doi: 10.1124/jpet.107.122242. Epub 2007 May 30. J Pharmacol Exp Ther. 2007. PMID: 17538006

7

Development and optimization of high-throughput in vitro protein phosphatase screening assays.

Tierno MB, Johnston PA, Foster C, Skoko JJ, Shinde SN, Shun TY, Lazo JS. Tierno MB, et al. Among authors: skoko jj. Nat Protoc. 2007;2(5):1134-44. doi: 10.1038/nprot.2007.155. Nat Protoc. 2007. PMID: 17546004

8

Development and implementation of a 384-well homogeneous fluorescence intensity high-throughput screening assay to identify mitogen-activated protein kinase phosphatase-1 dual-specificity protein phosphatase inhibitors.

Johnston PA, Foster CA, Shun TY, Skoko JJ, Shinde S, Wipf P, Lazo JS. Johnston PA, et al. Among authors: skoko jj. Assay Drug Dev Technol. 2007 Jun;5(3):319-32. doi: 10.1089/adt.2007.066. Assay Drug Dev Technol. 2007. PMID: 17638532

9

A cell-active inhibitor of mitogen-activated protein kinase phosphatases restores paclitaxel-induced apoptosis in dexamethasone-protected cancer cells.

Vogt A, McDonald PR, Tamewitz A, Sikorski RP, Wipf P, Skoko JJ 3rd, Lazo JS. Vogt A, et al. Among authors: skoko jj 3rd. Mol Cancer Ther. 2008 Feb;7(2):330-40. doi: 10.1158/1535-7163.MCT-07-2165. Epub 2008 Feb 1. Mol Cancer Ther. 2008. PMID: 18245669

10

Computational design, synthesis and biological evaluation of para-quinone-based inhibitors for redox regulation of the dual-specificity phosphatase Cdc25B.

Keinan S, Paquette WD, Skoko JJ, Beratan DN, Yang W, Shinde S, Johnston PA, Lazo JS, Wipf P. Keinan S, et al. Among authors: skoko jj. Org Biomol Chem. 2008 Sep 21;6(18):3256-63. doi: 10.1039/b806712k. Epub 2008 Jul 15. Org Biomol Chem. 2008. PMID: 18802630 Free PMC article.

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