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Function-dependent conformational changes of the ABCG2 multidrug transporter modify its interaction with a monoclonal antibody on the cell surface.
Ozvegy-Laczka C, Várady G, Köblös G, Ujhelly O, Cervenak J, Schuetz JD, Sorrentino BP, Koomen GJ, Váradi A, Német K, Sarkadi B. Ozvegy-Laczka C, et al. Among authors: varady g. J Biol Chem. 2005 Feb 11;280(6):4219-27. doi: 10.1074/jbc.M411338200. Epub 2004 Nov 22. J Biol Chem. 2005. PMID: 15557326 Free article.
Interaction with the 5D3 monoclonal antibody is regulated by intramolecular rearrangements but not by covalent dimer formation of the human ABCG2 multidrug transporter.
Ozvegy-Laczka C, Laczkó R, Hegedus C, Litman T, Várady G, Goda K, Hegedus T, Dokholyan NV, Sorrentino BP, Váradi A, Sarkadi B. Ozvegy-Laczka C, et al. Among authors: varady g. J Biol Chem. 2008 Sep 19;283(38):26059-70. doi: 10.1074/jbc.M803230200. Epub 2008 Jul 21. J Biol Chem. 2008. PMID: 18644784 Free PMC article.
High level functional expression of the ABCG2 multidrug transporter in undifferentiated human embryonic stem cells.
Apáti A, Orbán TI, Varga N, Németh A, Schamberger A, Krizsik V, Erdélyi-Belle B, Homolya L, Várady G, Padányi R, Karászi E, Kemna EW, Német K, Sarkadi B. Apáti A, et al. Among authors: varady g. Biochim Biophys Acta. 2008 Dec;1778(12):2700-9. doi: 10.1016/j.bbamem.2008.08.010. Epub 2008 Aug 20. Biochim Biophys Acta. 2008. PMID: 18793608 Free article.
Applying a "double-feature" promoter to identify cardiomyocytes differentiated from human embryonic stem cells following transposon-based gene delivery.
Orbán TI, Apáti A, Németh A, Varga N, Krizsik V, Schamberger A, Szebényi K, Erdei Z, Várady G, Karászi E, Homolya L, Német K, Gócza E, Miskey C, Mátés L, Ivics Z, Izsvák Z, Sarkadi B. Orbán TI, et al. Among authors: varady g. Stem Cells. 2009 May;27(5):1077-87. doi: 10.1002/stem.45. Stem Cells. 2009. PMID: 19415778
76 results