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Identification of a broad-spectrum azasordarin with improved pharmacokinetic properties.
Serrano-Wu MH, Laurent DR, Carroll TM, Dodier M, Gao Q, Gill P, Quesnelle C, Marinier A, Mazzucco CE, Regueiro-Ren A, Stickle TM, Wu D, Yang H, Yang Z, Zheng M, Zoeckler ME, Vyas DM, Balasubramanian BN. Serrano-Wu MH, et al. Among authors: wu d. Bioorg Med Chem Lett. 2003 Apr 17;13(8):1419-23. doi: 10.1016/s0960-894x(03)00161-6. Bioorg Med Chem Lett. 2003. PMID: 12668003
2-arylaminothiazoles as high-affinity corticotropin-releasing factor 1 receptor (CRF1R) antagonists: synthesis, binding studies and behavioral efficacy.
Dubowchik GM, Michne JA, Zuev D, Schwartz W, Scola PM, James CA, Ruediger EH, Pin SS, Burris KD, Balanda LA, Gao Q, Wu D, Fung L, Fiedler T, Browman KE, Taber MT, Zhang J. Dubowchik GM, et al. Among authors: wu d. Bioorg Med Chem Lett. 2003 Nov 17;13(22):3997-4000. doi: 10.1016/j.bmcl.2003.08.055. Bioorg Med Chem Lett. 2003. PMID: 14592493
Catalytic asymmetric syntheses of tyrosine surrogates.
Han X, Civiello RL, Fang H, Wu D, Gao Q, Chaturvedula PV, Macor JE, Dubowchik GM. Han X, et al. Among authors: wu d. J Org Chem. 2008 Nov 7;73(21):8502-10. doi: 10.1021/jo801577t. Epub 2008 Oct 15. J Org Chem. 2008. PMID: 18855485
Inhibitors of human immunodeficiency virus type 1 (HIV-1) attachment. 12. Structure-activity relationships associated with 4-fluoro-6-azaindole derivatives leading to the identification of 1-(4-benzoylpiperazin-1-yl)-2-(4-fluoro-7-[1,2,3]triazol-1-yl-1h-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione (BMS-585248).
Regueiro-Ren A, Xue QM, Swidorski JJ, Gong YF, Mathew M, Parker DD, Yang Z, Eggers B, D'Arienzo C, Sun Y, Malinowski J, Gao Q, Wu D, Langley DR, Colonno RJ, Chien C, Grasela DM, Zheng M, Lin PF, Meanwell NA, Kadow JF. Regueiro-Ren A, et al. Among authors: wu d, d arienzo c. J Med Chem. 2013 Feb 28;56(4):1656-69. doi: 10.1021/jm3016377. Epub 2013 Feb 7. J Med Chem. 2013. PMID: 23360431
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