Sakamoto K - Search Results

1

Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis.

McManus EJ, Sakamoto K, Armit LJ, Ronaldson L, Shpiro N, Marquez R, Alessi DR. McManus EJ, et al. Among authors: sakamoto k. EMBO J. 2005 Apr 20;24(8):1571-83. doi: 10.1038/sj.emboj.7600633. Epub 2005 Mar 24. EMBO J. 2005. PMID: 15791206 Free PMC article.

2

Role of TAPP1 and TAPP2 adaptor binding to PtdIns(3,4)P2 in regulating insulin sensitivity defined by knock-in analysis.

Wullschleger S, Wasserman DH, Gray A, Sakamoto K, Alessi DR. Wullschleger S, et al. Among authors: sakamoto k. Biochem J. 2011 Mar 1;434(2):265-74. doi: 10.1042/BJ20102012. Biochem J. 2011. PMID: 21204784 Free PMC article.

3

Investigation of LKB1 Ser431 phosphorylation and Cys433 farnesylation using mouse knockin analysis reveals an unexpected role of prenylation in regulating AMPK activity.

Houde VP, Ritorto MS, Gourlay R, Varghese J, Davies P, Shpiro N, Sakamoto K, Alessi DR. Houde VP, et al. Among authors: sakamoto k. Biochem J. 2014 Feb 15;458(1):41-56. doi: 10.1042/BJ20131324. Biochem J. 2014. PMID: 24295069 Free PMC article.

4

Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction.

Sakamoto K, McCarthy A, Smith D, Green KA, Grahame Hardie D, Ashworth A, Alessi DR. Sakamoto K, et al. EMBO J. 2005 May 18;24(10):1810-20. doi: 10.1038/sj.emboj.7600667. Epub 2005 May 5. EMBO J. 2005. PMID: 15889149 Free PMC article.

5

Role of the PDK1-PKB-GSK3 pathway in regulating glycogen synthase and glucose uptake in the heart.

Mora A, Sakamoto K, McManus EJ, Alessi DR. Mora A, et al. Among authors: sakamoto k. FEBS Lett. 2005 Jul 4;579(17):3632-8. doi: 10.1016/j.febslet.2005.05.040. FEBS Lett. 2005. Retraction in: FEBS Lett. 2024 Oct 24. doi: 10.1002/1873-3468.15044. PMID: 15961082 Free article. Retracted.

6

Evaluation of approaches to generation of tissue-specific knock-in mice.

Bayascas JR, Sakamoto K, Armit L, Arthur JS, Alessi DR. Bayascas JR, et al. Among authors: sakamoto k. J Biol Chem. 2006 Sep 29;281(39):28772-81. doi: 10.1074/jbc.M606789200. Epub 2006 Aug 3. J Biol Chem. 2006. PMID: 16887794 Free article.

7

Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice.

Huang X, Wullschleger S, Shpiro N, McGuire VA, Sakamoto K, Woods YL, McBurnie W, Fleming S, Alessi DR. Huang X, et al. Among authors: sakamoto k. Biochem J. 2008 Jun 1;412(2):211-21. doi: 10.1042/BJ20080557. Biochem J. 2008. PMID: 18387000

8

Use of Akt inhibitor and a drug-resistant mutant validates a critical role for protein kinase B/Akt in the insulin-dependent regulation of glucose and system A amino acid uptake.

Green CJ, Göransson O, Kular GS, Leslie NR, Gray A, Alessi DR, Sakamoto K, Hundal HS. Green CJ, et al. Among authors: sakamoto k. J Biol Chem. 2008 Oct 10;283(41):27653-27667. doi: 10.1074/jbc.M802623200. Epub 2008 Jul 31. J Biol Chem. 2008. PMID: 18669636 Free article.

9

How moderate changes in Akt T-loop phosphorylation impact on tumorigenesis and insulin resistance.

Wullschleger S, Sakamoto K, Johnstone L, Duce S, Fleming S, Alessi DR. Wullschleger S, et al. Among authors: sakamoto k. Dis Model Mech. 2011 Jan;4(1):95-103. doi: 10.1242/dmm.005603. Epub 2010 Oct 19. Dis Model Mech. 2011. PMID: 20959631 Free PMC article.

10

Regulation of the NKCC2 ion cotransporter by SPAK-OSR1-dependent and -independent pathways.

Richardson C, Sakamoto K, de los Heros P, Deak M, Campbell DG, Prescott AR, Alessi DR. Richardson C, et al. Among authors: sakamoto k. J Cell Sci. 2011 Mar 1;124(Pt 5):789-800. doi: 10.1242/jcs.077230. J Cell Sci. 2011. PMID: 21321328 Free PMC article.

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