Shpiro N - Search Results

1

Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis.

McManus EJ, Sakamoto K, Armit LJ, Ronaldson L, Shpiro N, Marquez R, Alessi DR. McManus EJ, et al. Among authors: shpiro n. EMBO J. 2005 Apr 20;24(8):1571-83. doi: 10.1038/sj.emboj.7600633. Epub 2005 Mar 24. EMBO J. 2005. PMID: 15791206 Free PMC article.

2

Glycogen synthase kinase-3 regulates IGFBP-1 gene transcription through the thymine-rich insulin response element.

Finlay D, Patel S, Dickson LM, Shpiro N, Marquez R, Rhodes CJ, Sutherland C. Finlay D, et al. Among authors: shpiro n. BMC Mol Biol. 2004 Sep 6;5:15. doi: 10.1186/1471-2199-5-15. BMC Mol Biol. 2004. PMID: 15350195 Free PMC article.

3

Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3.

Murray JT, Campbell DG, Morrice N, Auld GC, Shpiro N, Marquez R, Peggie M, Bain J, Bloomberg GB, Grahammer F, Lang F, Wulff P, Kuhl D, Cohen P. Murray JT, et al. Among authors: shpiro n. Biochem J. 2004 Dec 15;384(Pt 3):477-88. doi: 10.1042/BJ20041057. Biochem J. 2004. PMID: 15461589 Free PMC article.

4

BIRB796 inhibits all p38 MAPK isoforms in vitro and in vivo.

Kuma Y, Sabio G, Bain J, Shpiro N, Márquez R, Cuenda A. Kuma Y, et al. Among authors: shpiro n. J Biol Chem. 2005 May 20;280(20):19472-9. doi: 10.1074/jbc.M414221200. Epub 2005 Mar 8. J Biol Chem. 2005. PMID: 15755732 Free article.

5

Synthesis of an IGD peptidomimetic with motogenic activity.

Shpiro N, Ellis IR, Dines TJ, Schor AM, Schor SL, Norman DG, Marquez R. Shpiro N, et al. Mol Biosyst. 2005 Oct;1(4):318-20. doi: 10.1039/b509023g. Epub 2005 Aug 26. Mol Biosyst. 2005. PMID: 16880997

6

The selectivity of protein kinase inhibitors: a further update.

Bain J, Plater L, Elliott M, Shpiro N, Hastie CJ, McLauchlan H, Klevernic I, Arthur JS, Alessi DR, Cohen P. Bain J, et al. Among authors: shpiro n. Biochem J. 2007 Dec 15;408(3):297-315. doi: 10.1042/BJ20070797. Biochem J. 2007. PMID: 17850214 Free PMC article.

7

Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase.

Göransson O, McBride A, Hawley SA, Ross FA, Shpiro N, Foretz M, Viollet B, Hardie DG, Sakamoto K. Göransson O, et al. Among authors: shpiro n. J Biol Chem. 2007 Nov 9;282(45):32549-60. doi: 10.1074/jbc.M706536200. Epub 2007 Sep 12. J Biol Chem. 2007. PMID: 17855357 Free PMC article.

8

VX-680 inhibits Aurora A and Aurora B kinase activity in human cells.

Tyler RK, Shpiro N, Marquez R, Eyers PA. Tyler RK, et al. Among authors: shpiro n. Cell Cycle. 2007 Nov 15;6(22):2846-54. doi: 10.4161/cc.6.22.4940. Epub 2007 Aug 27. Cell Cycle. 2007. PMID: 18032922

9

Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice.

Huang X, Wullschleger S, Shpiro N, McGuire VA, Sakamoto K, Woods YL, McBurnie W, Fleming S, Alessi DR. Huang X, et al. Among authors: shpiro n. Biochem J. 2008 Jun 1;412(2):211-21. doi: 10.1042/BJ20080557. Biochem J. 2008. PMID: 18387000

10

Akt is efficiently activated by PIF-pocket- and PtdIns(3,4,5)P3-dependent mechanisms leading to resistance to PDK1 inhibitors.

Najafov A, Shpiro N, Alessi DR. Najafov A, et al. Among authors: shpiro n. Biochem J. 2012 Dec 1;448(2):285-95. doi: 10.1042/BJ20121287. Biochem J. 2012. PMID: 23030823

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