Alley M - Search Results

1

In vivo antitumor efficacy of 17-DMAG (17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride), a water-soluble geldanamycin derivative.

Hollingshead M, Alley M, Burger AM, Borgel S, Pacula-Cox C, Fiebig HH, Sausville EA. Hollingshead M, et al. Among authors: alley m. Cancer Chemother Pharmacol. 2005 Aug;56(2):115-25. doi: 10.1007/s00280-004-0939-2. Epub 2005 Mar 25. Cancer Chemother Pharmacol. 2005. PMID: 15791458

2

SJG-136 (NSC 694501), a novel rationally designed DNA minor groove interstrand cross-linking agent with potent and broad spectrum antitumor activity: part 2: efficacy evaluations.

Alley MC, Hollingshead MG, Pacula-Cox CM, Waud WR, Hartley JA, Howard PW, Gregson SJ, Thurston DE, Sausville EA. Alley MC, et al. Cancer Res. 2004 Sep 15;64(18):6700-6. doi: 10.1158/0008-5472.CAN-03-2942. Cancer Res. 2004. PMID: 15374987

3

Aryl hydrocarbon receptor activation of an antitumor aminoflavone: basis of selective toxicity for MCF-7 breast tumor cells.

Loaiza-Pérez AI, Kenney S, Boswell J, Hollingshead M, Alley MC, Hose C, Ciolino HP, Yeh GC, Trepel JB, Vistica DT, Sausville EA. Loaiza-Pérez AI, et al. Among authors: alley mc. Mol Cancer Ther. 2004 Jun;3(6):715-25. Mol Cancer Ther. 2004. PMID: 15210858

4

SJG-136 (NSC 694501), a novel rationally designed DNA minor groove interstrand cross-linking agent with potent and broad spectrum antitumor activity: part 1: cellular pharmacology, in vitro and initial in vivo antitumor activity.

Hartley JA, Spanswick VJ, Brooks N, Clingen PH, McHugh PJ, Hochhauser D, Pedley RB, Kelland LR, Alley MC, Schultz R, Hollingshead MG, Schweikart KM, Tomaszewski JE, Sausville EA, Gregson SJ, Howard PW, Thurston DE. Hartley JA, et al. Among authors: alley mc. Cancer Res. 2004 Sep 15;64(18):6693-9. doi: 10.1158/0008-5472.CAN-03-2941. Cancer Res. 2004. PMID: 15374986

5

Cucurbitacin E-induced disruption of the actin and vimentin cytoskeleton in prostate carcinoma cells.

Duncan KL, Duncan MD, Alley MC, Sausville EA. Duncan KL, et al. Among authors: alley mc. Biochem Pharmacol. 1996 Nov 22;52(10):1553-60. doi: 10.1016/s0006-2952(96)00557-6. Biochem Pharmacol. 1996. PMID: 8937470 Free article.

6

In vitro combination treatment with perifosine and UCN-01 demonstrates synergism against prostate (PC-3) and lung (A549) epithelial adenocarcinoma cell lines.

Dasmahapatra GP, Didolkar P, Alley MC, Ghosh S, Sausville EA, Roy KK. Dasmahapatra GP, et al. Clin Cancer Res. 2004 Aug 1;10(15):5242-52. doi: 10.1158/1078-0432.CCR-03-0534. Clin Cancer Res. 2004. PMID: 15297428

7

Morphological and immunocytochemical characteristics of human tumor cell lines for use in a disease-oriented anticancer drug screen.

Stinson SF, Alley MC, Kopp WC, Fiebig HH, Mullendore LA, Pittman AF, Kenney S, Keller J, Boyd MR. Stinson SF, et al. Among authors: alley mc. Anticancer Res. 1992 Jul-Aug;12(4):1035-53. Anticancer Res. 1992. PMID: 1503399

8

Inhibition of CDKs as a therapeutic modality.

Sausville EA, Johnson J, Alley M, Zaharevitz D, Senderowicz AM. Sausville EA, et al. Among authors: alley m. Ann N Y Acad Sci. 2000 Jun;910:207-21; discussion 221-2. doi: 10.1111/j.1749-6632.2000.tb06710.x. Ann N Y Acad Sci. 2000. PMID: 10911915

9

Fluorinated 2-(4-amino-3-methylphenyl)benzothiazoles induce CYP1A1 expression, become metabolized, and bind to macromolecules in sensitive human cancer cells.

Brantley E, Trapani V, Alley MC, Hose CD, Bradshaw TD, Stevens MF, Sausville EA, Stinson SF. Brantley E, et al. Drug Metab Dispos. 2004 Dec;32(12):1392-401. doi: 10.1124/dmd.104.001057. Epub 2004 Sep 8. Drug Metab Dispos. 2004. PMID: 15355884

10

Tyrphostin AG17, [(3,5-Di-tert-butyl-4-hydroxybenzylidene)- malononitrile], inhibits cell growth by disrupting mitochondria.

Burger AM, Kaur G, Alley MC, Supko JG, Malspeis L, Grever MR, Sausville EA. Burger AM, et al. Among authors: alley mc. Cancer Res. 1995 Jul 1;55(13):2794-9. Cancer Res. 1995. PMID: 7796405

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