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Evaluation of the activities of pyrimethamine analogs against Plasmodium vivax and Plasmodium falciparum dihydrofolate reductase-thymidylate synthase using in vitro enzyme inhibition and bacterial complementation assays.
Bunyarataphan S, Leartsakulpanich U, Taweechai S, Tarnchompoo B, Kamchonwongpaisan S, Yuthavong Y. Bunyarataphan S, et al. Among authors: tarnchompoo b. Antimicrob Agents Chemother. 2006 Nov;50(11):3631-7. doi: 10.1128/AAC.00448-06. Epub 2006 Sep 5. Antimicrob Agents Chemother. 2006. PMID: 16954316 Free PMC article.
Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target.
Yuthavong Y, Tarnchompoo B, Vilaivan T, Chitnumsub P, Kamchonwongpaisan S, Charman SA, McLennan DN, White KL, Vivas L, Bongard E, Thongphanchang C, Taweechai S, Vanichtanankul J, Rattanajak R, Arwon U, Fantauzzi P, Yuvaniyama J, Charman WN, Matthews D. Yuthavong Y, et al. Among authors: tarnchompoo b. Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):16823-8. doi: 10.1073/pnas.1204556109. Epub 2012 Oct 3. Proc Natl Acad Sci U S A. 2012. PMID: 23035243 Free PMC article.
Flexible diaminodihydrotriazine inhibitors of Plasmodium falciparum dihydrofolate reductase: Binding strengths, modes of binding and their antimalarial activities.
Kamchonwongpaisan S, Charoensetakul N, Srisuwannaket C, Taweechai S, Rattanajak R, Vanichtanankul J, Vitsupakorn D, Arwon U, Thongpanchang C, Tarnchompoo B, Vilaivan T, Yuthavong Y. Kamchonwongpaisan S, et al. Among authors: tarnchompoo b. Eur J Med Chem. 2020 Jun 1;195:112263. doi: 10.1016/j.ejmech.2020.112263. Epub 2020 Mar 25. Eur J Med Chem. 2020. PMID: 32294614
18 results