Lazo JS - Search Results

1

MKP-8, a novel MAPK phosphatase that inhibits p38 kinase.

Vasudevan SA, Skoko J, Wang K, Burlingame SM, Patel PN, Lazo JS, Nuchtern JG, Yang J. Vasudevan SA, et al. Among authors: lazo js. Biochem Biophys Res Commun. 2005 May 6;330(2):511-8. doi: 10.1016/j.bbrc.2005.03.028. Biochem Biophys Res Commun. 2005. PMID: 15796912

2

The benzo[c]phenanthridine alkaloid, sanguinarine, is a selective, cell-active inhibitor of mitogen-activated protein kinase phosphatase-1.

Vogt A, Tamewitz A, Skoko J, Sikorski RP, Giuliano KA, Lazo JS. Vogt A, et al. Among authors: lazo js. J Biol Chem. 2005 May 13;280(19):19078-86. doi: 10.1074/jbc.M501467200. Epub 2005 Mar 7. J Biol Chem. 2005. PMID: 15753082 Free article.

3

Redox regulation of Cdc25B by cell-active quinolinediones.

Brisson M, Nguyen T, Wipf P, Joo B, Day BW, Skoko JS, Schreiber EM, Foster C, Bansal P, Lazo JS. Brisson M, et al. Among authors: lazo js. Mol Pharmacol. 2005 Dec;68(6):1810-20. doi: 10.1124/mol.105.016360. Epub 2005 Sep 9. Mol Pharmacol. 2005. PMID: 16155209

4

Novel benzofuran inhibitors of human mitogen-activated protein kinase phosphatase-1.

Lazo JS, Nunes R, Skoko JJ, Queiroz de Oliveira PE, Vogt A, Wipf P. Lazo JS, et al. Bioorg Med Chem. 2006 Aug 15;14(16):5643-50. doi: 10.1016/j.bmc.2006.04.036. Epub 2006 May 15. Bioorg Med Chem. 2006. PMID: 16698271

5

Biological evaluation of newly synthesized quinoline-5,8-quinones as Cdc25B inhibitors.

Cossy J, Belotti D, Brisson M, Skoko JJ, Wipf P, Lazo JS. Cossy J, et al. Among authors: lazo js. Bioorg Med Chem. 2006 Sep 15;14(18):6283-7. doi: 10.1016/j.bmc.2006.05.053. Epub 2006 Jun 16. Bioorg Med Chem. 2006. PMID: 16782352

6

Structurally unique inhibitors of human mitogen-activated protein kinase phosphatase-1 identified in a pyrrole carboxamide library.

Lazo JS, Skoko JJ, Werner S, Mitasev B, Bakan A, Koizumi F, Yellow-Duke A, Bahar I, Brummond KM. Lazo JS, et al. J Pharmacol Exp Ther. 2007 Sep;322(3):940-7. doi: 10.1124/jpet.107.122242. Epub 2007 May 30. J Pharmacol Exp Ther. 2007. PMID: 17538006

7

Development and optimization of high-throughput in vitro protein phosphatase screening assays.

Tierno MB, Johnston PA, Foster C, Skoko JJ, Shinde SN, Shun TY, Lazo JS. Tierno MB, et al. Among authors: lazo js. Nat Protoc. 2007;2(5):1134-44. doi: 10.1038/nprot.2007.155. Nat Protoc. 2007. PMID: 17546004

8

Development and implementation of a 384-well homogeneous fluorescence intensity high-throughput screening assay to identify mitogen-activated protein kinase phosphatase-1 dual-specificity protein phosphatase inhibitors.

Johnston PA, Foster CA, Shun TY, Skoko JJ, Shinde S, Wipf P, Lazo JS. Johnston PA, et al. Among authors: lazo js. Assay Drug Dev Technol. 2007 Jun;5(3):319-32. doi: 10.1089/adt.2007.066. Assay Drug Dev Technol. 2007. PMID: 17638532

9

A cell-active inhibitor of mitogen-activated protein kinase phosphatases restores paclitaxel-induced apoptosis in dexamethasone-protected cancer cells.

Vogt A, McDonald PR, Tamewitz A, Sikorski RP, Wipf P, Skoko JJ 3rd, Lazo JS. Vogt A, et al. Among authors: lazo js. Mol Cancer Ther. 2008 Feb;7(2):330-40. doi: 10.1158/1535-7163.MCT-07-2165. Epub 2008 Feb 1. Mol Cancer Ther. 2008. PMID: 18245669

10

Computational design, synthesis and biological evaluation of para-quinone-based inhibitors for redox regulation of the dual-specificity phosphatase Cdc25B.

Keinan S, Paquette WD, Skoko JJ, Beratan DN, Yang W, Shinde S, Johnston PA, Lazo JS, Wipf P. Keinan S, et al. Among authors: lazo js. Org Biomol Chem. 2008 Sep 21;6(18):3256-63. doi: 10.1039/b806712k. Epub 2008 Jul 15. Org Biomol Chem. 2008. PMID: 18802630 Free PMC article.

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