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Induction of CYP1A in the beagle dog by an inhibitor of kinase insert domain-containing receptor: differential effects in vitro and in vivo on mRNA and functional activity.
Gibson CR, Lin C, Singh R, Brown CM, Richards K, Brunner J, Michel K, Adelsberger J, Carlini E, Boothe-Genthe C, Raab C, Luu M, Michael A, Parikh M, Ciecko P, Subramanian R, Krolikowski P, Rodrigues AD, Baillie TA, Rushmore TH. Gibson CR, et al. Among authors: subramanian r. Drug Metab Dispos. 2005 Jul;33(7):1044-51. doi: 10.1124/dmd.105.003913. Epub 2005 Apr 15. Drug Metab Dispos. 2005. PMID: 15833927
Metabolism and disposition of a potent and selective GABA-Aalpha2/3 receptor agonist in healthy male volunteers.
Polsky-Fisher SL, Vickers S, Cui D, Subramanian R, Arison BH, Agrawal NG, Goel TV, Vessey LK, Murphy MG, Lasseter KC, Simpson RC, Vega JM, Rodrigues AD. Polsky-Fisher SL, et al. Among authors: subramanian r. Drug Metab Dispos. 2006 Jun;34(6):1004-11. doi: 10.1124/dmd.105.008193. Epub 2006 Mar 1. Drug Metab Dispos. 2006. PMID: 16510541 Clinical Trial.
Bioactivation of 2,3-diaminopyridine-containing bradykinin B1 receptor antagonists: irreversible binding to liver microsomal proteins and formation of glutathione conjugates.
Tang C, Subramanian R, Kuo Y, Krymgold S, Lu P, Kuduk SD, Ng C, Feng DM, Elmore C, Soli E, Ho J, Bock MG, Baillie TA, Prueksaritanont T. Tang C, et al. Among authors: subramanian r. Chem Res Toxicol. 2005 Jun;18(6):934-45. doi: 10.1021/tx0500427. Chem Res Toxicol. 2005. PMID: 15962928
Effects of fibrates on metabolism of statins in human hepatocytes.
Prueksaritanont T, Tang C, Qiu Y, Mu L, Subramanian R, Lin JH. Prueksaritanont T, et al. Among authors: subramanian r. Drug Metab Dispos. 2002 Nov;30(11):1280-7. doi: 10.1124/dmd.30.11.1280. Drug Metab Dispos. 2002. PMID: 12386136
754 results